Protein Alignment Dh31-R and ghrhra

DIOPT Version :10

• Sequence 1: NP_001260951.1
• Gene: Dh31-R / 36475
• FlyBaseID: FBgn0052843
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_001124524.1
• Gene: ghrhra / 541314
• ZFINID: ZDB-GENE-050315-2
• Length: 432
• Species: Danio rerio
• Alignment Length: 388
• Identity: 112/388 - (28%)
• Similarity: 180/388 - (46%)
• Gaps: 51/388 - (13%)

  Fly    66 THCAGTFDGWLCWPDTAVGTSAYELCPDFITGFDPAR-YAHKECGLDGEWFKHPLTNKTWSN--- 126
            |.|...:||..||.....|......|.|........: :.::.|..:|           |::
Zfish    51 TGCGTDWDGIRCWHTANTGQLINVSCSDVFQHISNTQGFIYRNCVSNG-----------WTDPYP 104

  Fly   127 -YTTCVNLED-------LNWRHTVNLISEVGYGTSLLAILLSLAILGYFKSLKCARITLHMNLFA 183
             |......||       ..:..|:..:...||.|||::::.::.|...|:...|.|..:|:|||.
Zfish   105 PYEEACAFEDDSESGTVTTYLSTLKQLYTAGYATSLISLITAVIIFTCFRKFHCTRNYIHINLFV 169

  Fly   184 SFAANNSLWLVWYLLVMPNSELLH--QSPMRCVALHITLHYFLLSNYSWMLCEGFYLHTVLVAAF 246
            ||....|...:...::..:....|  .|.:.|.:......:.:|:||.|:|.||.||.|:|...|
Zfish   170 SFILRASAVFIKGTVLFSDETQDHCLMSTVLCKSAVTFFQFCILTNYFWLLVEGLYLQTLLALTF 234

  Fly   247 ISEKRLVKWLIAFGWGSPAIVIFVYSMARGLGGTPEDNRHCW--MNQTNYQNILMVPVCISMFLN 309
            :|:::...|.|..|||.|::|:.|:.:.|..    .|||.||  .:.||...|:..|:..|:|.|
Zfish   235 VSQRKYFWWYILIGWGVPSVVLVVWVLTRQF----YDNRGCWDDTDNTNIWWIIKGPITASLFTN 295

  Fly   310 LLFLCNIVRVVLLKLNAPASIQGSCGPSRT--VLQAFRATLLLVPLLGLQYILTPFRPAPKHPWE 372
            ::...|::|:::.||.:|     ..|.:.|  .::..::||.|:||.|:.|.|..|.|      |
Zfish   296 IIIFLNVIRILVQKLKSP-----GVGGNDTGHFMRLAKSTLFLIPLFGMHYTLFAFLP------E 349

  Fly   373 NTYEIISAF----TASFQGLCVAILFCFCNGEVIAQMKRK---WRMMCFSNRPRTNSYTATQV 428
            ||.|||..:    ..||||..||:|:||.||||.|::||:   |......:..:....|.||:
Zfish   350 NTGEIIRFYIELGLGSFQGFVVALLYCFLNGEVQAELKRRLWTWLTQTHLSPCKKRRVTVTQI 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh31-R	NP_001260951.1	HRM	65..132	CDD:397086	13/70 (19%)
		7tmB1_NPR_B4_insect-like	139..411	CDD:320388	94/284 (33%)
		TM helix 1	141..166	CDD:320388	7/24 (29%)
		TM helix 2	175..197	CDD:320388	7/21 (33%)
		TM helix 3	214..241	CDD:320388	9/26 (35%)
		TM helix 4	253..273	CDD:320388	8/19 (42%)
		TM helix 5	291..320	CDD:320388	9/28 (32%)
		TM helix 6	339..366	CDD:320388	10/28 (36%)
		TM helix 7	373..398	CDD:320388	14/28 (50%)
ghrhra	NP_001124524.1	HRM	52..113	CDD:397086	12/71 (17%)
		7tmB1_GHRHR2	125..392	CDD:320399	93/281 (33%)
		TM helix 1	127..152	CDD:320399	7/24 (29%)
		TM helix 2	161..183	CDD:320399	7/21 (33%)
		TM helix 3	202..229	CDD:320399	9/26 (35%)
		TM helix 4	241..261	CDD:320399	8/19 (42%)
		TM helix 5	277..306	CDD:320399	9/28 (32%)
		TM helix 6	322..349	CDD:320399	10/32 (31%)
		TM helix 7	354..379	CDD:320399	11/24 (46%)