Protein Alignment Dh31-R and calcrla

DIOPT Version :10

• Sequence 1: NP_001260951.1
• Gene: Dh31-R / 36475
• FlyBaseID: FBgn0052843
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_001004010.2
• Gene: calcrla / 445508
• ZFINID: ZDB-GENE-040822-26
• Length: 474
• Species: Danio rerio
• Alignment Length: 380
• Identity: 154/380 - (40%)
• Similarity: 221/380 - (58%)
• Gaps: 23/380 - (6%)

  Fly    65 GTHCAGTFDGWLCWPDTAVGTSAYELCPDFITGFDPARYAHKECGLDGEWFKHPLTNKTWSNYTT 129
            |..|..|:||||||.||..|.::.:.|||:...|||.....|.|...|:||.||.:|:||:|:|.
Zfish    74 GPVCNRTWDGWLCWDDTEAGITSEQHCPDYFQDFDPTEMVTKICTESGQWFLHPESNRTWTNFTR 138

  Fly   130 CVNLEDLNWRHT-VNL--ISEVGYGTSLLAILLSLAILGYFKSLKCARITLHMNLFASFAANNSL 191
            | ||.....|.| :||  ::.:|:|.||.::.:||.|..:||||.|.|||||.|||.||..|:.:
Zfish   139 C-NLHTTEGRRTAMNLFYLALIGHGLSLTSLFISLGIFFHFKSLSCQRITLHKNLFFSFVLNSII 202

  Fly   192 WLVWYLLVMPNSELLHQSPMRCVALHITLHYFLLSNYSWMLCEGFYLHTVLVAAFISEKRLVKWL 256
            .::|...|..|.||:.|:|:.|........|....||.||||||.||||::|.|..:||:.:.|.
Zfish   203 TIIWLTAVANNQELVQQNPISCKISQFIHLYIFGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWY 267

  Fly   257 IAFGWGSPAIVIFVYSMARGLGGTPEDNRHCWM-NQTNYQNILMVPVCISMFLNLLFLCNIVRVV 320
            ...|||.|.|...::::||..    ..|.:||: :.|:...|:..|:|.:|.:||.||.|||||:
Zfish   268 YLLGWGFPLIPATIHAVARSY----YYNDNCWISSNTSLLYIIHGPICAAMLVNLFFLLNIVRVL 328

  Fly   321 LLKLNAPASIQGSCGPSRTVLQAFRATLLLVPLLGLQYILTPFRPAPKHPWENTYEIISAFTASF 385
            :.||......:.|     ..::|.||||:||||||:||:|.|::|:.:...| .|:.|......:
Zfish   329 ITKLKVTHQAESS-----LYMKAVRATLILVPLLGIQYVLLPYKPSGRVSAE-IYDYIMHILMHY 387

  Fly   386 QGLCVAILFCFCNGEVIAQMKRKWRM--------MCFSNRPRTNSYTATQVSFVR 432
            |||.||.:|||.||||.|.::|.|..        :..|:..|:.||||:.::.|:
Zfish   388 QGLLVATIFCFFNGEVQAVLRRHWNQYRIQFGSTITQSDALRSASYTASSITEVQ 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh31-R	NP_001260951.1	HRM	65..132	CDD:397086	31/66 (47%)
		7tmB1_NPR_B4_insect-like	139..411	CDD:320388	114/275 (41%)
		TM helix 1	141..166	CDD:320388	10/27 (37%)
		TM helix 2	175..197	CDD:320388	11/21 (52%)
		TM helix 3	214..241	CDD:320388	12/26 (46%)
		TM helix 4	253..273	CDD:320388	6/19 (32%)
		TM helix 5	291..320	CDD:320388	13/28 (46%)
		TM helix 6	339..366	CDD:320388	15/26 (58%)
		TM helix 7	373..398	CDD:320388	10/24 (42%)
calcrla	NP_001004010.2	HRM	74..139	CDD:397086	30/64 (47%)
		7tmB1_calcitonin_R	150..423	CDD:341343	112/282 (40%)
		TM helix 1	152..177	CDD:341343	9/24 (38%)
		TM helix 2	186..208	CDD:341343	11/21 (52%)
		TM helix 3	225..252	CDD:341343	12/26 (46%)
		TM helix 4	264..284	CDD:341343	6/19 (32%)
		TM helix 5	299..328	CDD:341343	13/28 (46%)
		TM helix 6	342..369	CDD:341343	15/26 (58%)
		TM helix 7	375..400	CDD:341343	11/25 (44%)