DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dh31-R and Fbxo46

DIOPT Version :9

Sequence 1:	NP_001260951.1	Gene:	Dh31-R / 36475	FlyBaseID:	FBgn0052843	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_001020813.1	Gene:	Fbxo46 / 292686	RGDID:	1308393	Length:	603	Species:	Rattus norvegicus

Alignment Length:	231	Identity:	48/231 - (20%)
Similarity:	68/231 - (29%)	Gaps:	80/231 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   409 WRMMCFS----NRPRTNSYTATQVSFVRCGPPL---------PGEEKVXLKDMSAKRRASAGPQH 460
            |....||    |:||..|.|..        ||:         |......|:.......|.|....
  Rat    12 WCPRPFSKYSQNQPRPPSATLK--------PPVCPDTSSGTEPDHRPAHLESTPPALAAEAPTSQ 68

  Fly   461 HQPHHQSHQLST----DQQR-------------------------ARSQSLASSSSFLEGWRDRM 496
            |.|     .|||    |:.|                         ....|.|||......|....
  Rat    69 HAP-----LLSTAASGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDS 128

  Fly   497 PFLKRRQTIDHSRQSQPLMEEGGETVGQAKSAPGAVDRPTL------MTTIAEDVA----ETGTA 551
            ...|||:......::.|  ::||:     :..|.....||.      :.::||.||    ....|
  Rat   129 SKAKRRRRCLEPTKAPP--DQGGQ-----EGTPATEVAPTSSGDDVDLLSVAEMVALVEQRAALA 186

  Fly   552 ATSHAASTSDAAAAAAVGAGGATGAEEGHP-NGMGT 586
            ..|:...::.|...       ...||:|.| .|:|:
  Rat   187 LQSYPRPSTPAPVV-------FVSAEQGGPAKGLGS 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dh31-R	NP_001260951.1	HRM	65..132	CDD:280888
Dh31-R	NP_001260951.1	7tm_4	140..390	CDD:304433
Fbxo46	NP_001020813.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	20..55		9/42 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	111..163		14/58 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	235..301
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	332..359
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	396..442
		F-box-like	473..>507	CDD:403981
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4564
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900