Protein Alignment Dh31-R and Vipr1

DIOPT Version :10

• Sequence 1: NP_001260951.1
• Gene: Dh31-R / 36475
• FlyBaseID: FBgn0052843
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_036817.1
• Gene: Vipr1 / 24875
• RGDID: 3961
• Length: 459
• Species: Rattus norvegicus
• Alignment Length: 430
• Identity: 126/430 - (29%)
• Similarity: 208/430 - (48%)
• Gaps: 79/430 - (18%)

  Fly    66 THCAGTFDGWLCWPDTAVGTSAYELCPDFITGFDPARYAHKECGLDGEWFKHPLTNKTWSN---- 126
            |.|:..:|...|||.|..|.:....||.....|.|         :.|.......|.:.||.
  Rat    61 TGCSKMWDNLTCWPTTPRGQAVVLDCPLIFQLFAP---------IHGYNISRSCTEEGWSQLEPG 116

  Fly   127 -YTTCVNLED----------LNWRHTVNLISEVGYGTSLLAILLSLAILGYFKSLKCARITLHMN 180
             |.....|.|          ..:.:||.....:||..||.::|:::|||..|:.|.|.|..:||:
  Rat   117 PYHIACGLNDRASSLDEQQQTKFYNTVKTGYTIGYSLSLASLLVAMAILSLFRKLHCTRNYIHMH 181

  Fly   181 LFASFAANNSLWLVWYLLVMPNSELLH--QSPMRCVALHITLHYFLLSNYSWMLCEGFYLHTVLV 243
            ||.||....:...:..:.:..:.|:.|  ::.:.|.|..:...|.:::|:.|:|.||.||:|:|.
  Rat   182 LFMSFILRATAVFIKDMALFNSGEIDHCSEASVGCKAAVVFFQYCVMANFFWLLVEGLYLYTLLA 246

  Fly   244 AAFISEKRLVKWLIAFGWGSPAIVIFVYSMAR----GLGGTPEDNRHCW---MNQTNYQNILMVP 301
            .:|.||::.....|..|||.|::.|.::::.|    ..|        ||   :|.:.:. |:..|
  Rat   247 VSFFSERKYFWGYILIGWGVPSVFITIWTVVRIYFEDFG--------CWDTIINSSLWW-IIKAP 302

  Fly   302 VCISMFLN-LLFLCNIVRVVLLKLNAPASIQGSCGP-SRTVLQAFRATLLLVPLLGLQYILTPFR 364
            :.:|:.:| :||:| |:|:::.||..|...:....| ||..    ::||||:||.|:.|::..|.
  Rat   303 ILLSILVNFVLFIC-IIRILVQKLRPPDIGKNDSSPYSRLA----KSTLLLIPLFGIHYVMFAFF 362

  Fly   365 PAP-KHPWENTYEIISAFTASFQGLCVAILFCFCNGEVIAQMKRKWR------MMCFSNRPR--- 419
            |.. |...:..:|::   ..||||..||||:||.||||.|:::||||      ::.:|::.:
  Rat   363 PDNFKAQVKMVFELV---VGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWSSKSQHPW 424

  Fly   420 --TNSYT-ATQVSFV-RCGPPLPGEEKVXLKDMSAKRRAS 455
              :|..| :||||.: |..|             ||:|.:|
  Rat   425 GGSNGATCSTQVSMLTRVSP-------------SARRSSS 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh31-R	NP_001260951.1	HRM	65..132	CDD:397086	17/70 (24%)
		7tmB1_NPR_B4_insect-like	139..411	CDD:320388	94/289 (33%)
		TM helix 1	141..166	CDD:320388	10/24 (42%)
		TM helix 2	175..197	CDD:320388	6/21 (29%)
		TM helix 3	214..241	CDD:320388	9/26 (35%)
		TM helix 4	253..273	CDD:320388	6/19 (32%)
		TM helix 5	291..320	CDD:320388	9/29 (31%)
		TM helix 6	339..366	CDD:320388	9/26 (35%)
		TM helix 7	373..398	CDD:320388	11/24 (46%)
Vipr1	NP_036817.1	HormR	59..130	CDD:214468	19/77 (25%)
		7tmB1_VIP-R1	140..407	CDD:320397	93/283 (33%)
		TM helix 1	142..167	CDD:320397	10/24 (42%)
		TM helix 2	176..198	CDD:320397	6/21 (29%)
		TM helix 3	217..244	CDD:320397	9/26 (35%)
		TM helix 4	256..276	CDD:320397	6/19 (32%)
		TM helix 5	292..321	CDD:320397	10/30 (33%)
		TM helix 6	337..364	CDD:320397	12/30 (40%)
		TM helix 7	369..394	CDD:320397	11/27 (41%)