Protein Alignment Dh31-R and seb-3

DIOPT Version :10

• Sequence 1: NP_001260951.1
• Gene: Dh31-R / 36475
• FlyBaseID: FBgn0052843
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_510496.1
• Gene: seb-3 / 181598
• WormBaseID: WBGene00007664
• Length: 454
• Species: Caenorhabditis elegans
• Alignment Length: 475
• Identity: 116/475 - (24%)
• Similarity: 203/475 - (42%)
• Gaps: 79/475 - (16%)

  Fly    42 AACETRLNASGQLAGSGGPGAEAGTHCAGTFDGWLCWPDTAVGTSAYELCP-DFITGFDPA---- 101
            |||:............||        |:..||..|||....:|......|| .|.|.....
 Worm    10 AACQELKKLENSSYNPGG--------CSVDFDKSLCWASAHIGQQMTRDCPFTFCTAIPGCEEIK 66

  Fly   102 -RY-AHKECGLDGEWFKHPLTNKTWSNYTTCVNLEDLNWRHTV------------NLISEVGYGT 152
             || ..:.|...|.|..        ||||.|:.:.: .:...:            :|:..|....
 Worm    67 DRYMVSRNCNSMGVWQD--------SNYTMCIKVVE-EYAQCLQGFCRVCPDVLRDLVISVSLTL 122

  Fly   153 SLLAILL---SLAILGYFKSLKCARITLHMNLFASFAANNSLWLVWYLLVMPN--SELLHQSPMR 212
            |.::::|   ::.:...|.|::|.|:::|.||..:|....::..:|.::...|  .:....:|:.
 Worm   123 SFVSVILLVAAIVLFSIFDSIQCRRLSIHKNLATAFVFRFAVLAIWTIVQTTNVFQDCTRLTPLP 187

  Fly   213 -------CVALHITLHYFLLSNYSWMLCEGFYLHTVLVAAFISEKRLVKW--LIAFGWGSPAIVI 268
                   |.|:...:.||.:::..|||.||.:|:: ....|........|  .:|.|||.|.:|:
 Worm   188 LWDYEWICKAILWFVIYFNVASVMWMLIEGAFLYS-RFTVFAMRHSDAPWSLYLACGWGVPFVVV 251

  Fly   269 FVYSMARGLGGTPEDNRHCWM--NQTNYQNILMVPVCISMFLNLLFLCNIVRVVLLKLNAPASIQ 331
            ..:::......:.:.|..||:  .|..:..||...:..::.:||:||..||.:::.||....|.:
 Worm   252 TAWALVHQYISSQQTNSFCWLPYAQGLHLWILAGTMGSALIMNLIFLLMIVVILVQKLRTENSAE 316

  Fly   332 GSCGPSRTVLQAFRATLLLVPLLGLQYILTPFRPAPKHPWENTYEIISAFTASFQGLCVAILFCF 396
                 |:.:.:..:||||||||||:..|  |....|:|| .:.|.:.||.....||:.:|:|:||
 Worm   317 -----SKKIWRTIKATLLLVPLLGISNI--PLFYEPEHP-SSVYMLGSAILQHSQGIFIAVLYCF 373

  Fly   397 CNGEVIAQMKRKWRMMCFS-----NRPRT-NSYTATQVSFVRCGPPLPGEEKVXLKDMSAKRRAS 455
            .|.|:...:||:...:.|.     ||..| .:|.....:..:.|.|        :::|:..:...
 Worm   374 LNSEIQGALKRQLSKVPFEFFKTRNRFETERTYVPEARNATKNGVP--------MEEMNKTKNIE 430

  Fly   456 AGPQHHQPHHQSHQLSTDQQ 475
            :|    :......|:||.:|
 Worm   431 SG----ENTESQDQVSTGKQ 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh31-R	NP_001260951.1	HRM	65..132	CDD:397086	21/73 (29%)
		7tmB1_NPR_B4_insect-like	139..411	CDD:320388	77/299 (26%)
		TM helix 1	141..166	CDD:320388	4/39 (10%)
		TM helix 2	175..197	CDD:320388	5/21 (24%)
		TM helix 3	214..241	CDD:320388	9/26 (35%)
		TM helix 4	253..273	CDD:320388	7/21 (33%)
		TM helix 5	291..320	CDD:320388	9/28 (32%)
		TM helix 6	339..366	CDD:320388	12/26 (46%)
		TM helix 7	373..398	CDD:320388	9/24 (38%)
seb-3	NP_510496.1	HRM	27..90	CDD:397086	21/78 (27%)
		7tmB1_hormone_R	112..388	CDD:341321	77/284 (27%)
		TM helix 1	114..139	CDD:341321	4/24 (17%)
		TM helix 2	148..170	CDD:341321	5/21 (24%)
		TM helix 3	196..223	CDD:341321	9/27 (33%)
		TM helix 4	236..256	CDD:341321	7/19 (37%)
		TM helix 5	276..305	CDD:341321	9/28 (32%)
		TM helix 6	319..346	CDD:341321	12/28 (43%)
		TM helix 7	350..375	CDD:341321	9/24 (38%)