DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dh31-R and Ghrhr

DIOPT Version :9

Sequence 1:NP_001260951.1 Gene:Dh31-R / 36475 FlyBaseID:FBgn0052843 Length:604 Species:Drosophila melanogaster
Sequence 2:XP_036021736.1 Gene:Ghrhr / 14602 MGIID:95710 Length:444 Species:Mus musculus


Alignment Length:365 Identity:96/365 - (26%)
Similarity:141/365 - (38%) Gaps:89/365 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    62 AEAGTH-----CAGTFDGWLCWPDTAVGTSAYELCPDFITGFDPARYAHKECGLDGEWFKHPLTN 121
            |..||:     |.||:||.||||.|..|......||:|.:.|          |.|..:.|...|.
Mouse    44 AAEGTNNTSLGCPGTWDGLLCWPPTGSGQWVSLPCPEFFSHF----------GSDTGFVKRDCTI 98

  Fly   122 KTWSN----Y-TTC-VNLE----DLNWRHTVNLISEVGYGTSLLAILLSLAILGYFKSLKCARIT 176
            ..|||    | ..| |.||    :.::..||.:|...|:..|::|:.:::|||...:.|.|.|..
Mouse    99 TGWSNPFPPYPVACPVPLELLTKEKSYFSTVKIIYTTGHSISIVALCVAIAILVALRRLHCPRNY 163

  Fly   177 LHMNLFASFAANNSLWLVWYLLVMPNSELLH--QSPMRCVALHITLHYFLLSNYSWMLCEGFYLH 239
            :|..|||:|....|...:....:.......|  .|.:.|.......|...::|:||:|.|..||.
Mouse   164 IHTQLFATFILKASAVFLKDAAIFQGDSTDHCSMSTVLCKVSVAISHLATMTNFSWLLAEAVYLS 228

  Fly   240 TVLVAAFISEKRLVKWLIAFGWGSPAIVIFVYSMARGLGGT------PEDNRHCW--MNQTNYQN 296
            .:|.:.....|....||:..|||.|.:..          ||      ..::..||  .|.:....
Mouse   229 CLLASTSPRSKPAFWWLVLAGWGLPVLCT----------GTWVGCKLAFEDTECWDLDNSSPCWW 283

  Fly   297 ILMVPVCISMFLNLLFLCNIVRVVLLKLNAPASIQGSCGPSRTVLQAFRATLLLVPLLGL----Q 357
            |:..|:.:|:.:|.....||:.::|.||. ||  ||                      ||    |
Mouse   284 IIKGPIVLSVGVNFGLFLNIICILLRKLE-PA--QG----------------------GLHTRAQ 323

  Fly   358 YILTPFRPAPKHPWENTYEIISAFTASFQGLCVAILFCFC 397
            |            |  .:..:.|.|.... :||.:..|.|
Mouse   324 Y------------W--YHSCVCACTCGCV-VCVCVCVCVC 348

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dh31-RNP_001260951.1 HRM 65..132 CDD:280888 26/77 (34%)
7tm_4 140..390 CDD:304433 62/263 (24%)
GhrhrXP_036021736.1 HRM 53..112 CDD:397086 23/68 (34%)
7tm_GPCRs 126..>325 CDD:421689 59/245 (24%)
TM helix 1 128..153 CDD:410628 9/24 (38%)
TM helix 2 162..184 CDD:410628 6/21 (29%)
TM helix 3 203..230 CDD:410628 8/26 (31%)
TM helix 4 242..262 CDD:410628 8/29 (28%)
TM helix 5 278..307 CDD:410628 6/28 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4564
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X66
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.810

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