Protein Alignment Dh31-R and Ghrhr

DIOPT Version :10

• Sequence 1: NP_001260951.1
• Gene: Dh31-R / 36475
• FlyBaseID: FBgn0052843
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: XP_036021736.1
• Gene: Ghrhr / 14602
• MGIID: 95710
• Length: 444
• Species: Mus musculus
• Alignment Length: 365
• Identity: 96/365 - (26%)
• Similarity: 141/365 - (38%)
• Gaps: 89/365 - (24%)

  Fly    62 AEAGTH-----CAGTFDGWLCWPDTAVGTSAYELCPDFITGFDPARYAHKECGLDGEWFKHPLTN 121
            |..||:     |.||:||.||||.|..|......||:|.:.|          |.|..:.|...|.
Mouse    44 AAEGTNNTSLGCPGTWDGLLCWPPTGSGQWVSLPCPEFFSHF----------GSDTGFVKRDCTI 98

  Fly   122 KTWSN----Y-TTC-VNLE----DLNWRHTVNLISEVGYGTSLLAILLSLAILGYFKSLKCARIT 176
            ..|||    | ..| |.||    :.::..||.:|...|:..|::|:.:::|||...:.|.|.|..
Mouse    99 TGWSNPFPPYPVACPVPLELLTKEKSYFSTVKIIYTTGHSISIVALCVAIAILVALRRLHCPRNY 163

  Fly   177 LHMNLFASFAANNSLWLVWYLLVMPNSELLH--QSPMRCVALHITLHYFLLSNYSWMLCEGFYLH 239
            :|..|||:|....|...:....:.......|  .|.:.|.......|...::|:||:|.|..||.
Mouse   164 IHTQLFATFILKASAVFLKDAAIFQGDSTDHCSMSTVLCKVSVAISHLATMTNFSWLLAEAVYLS 228

  Fly   240 TVLVAAFISEKRLVKWLIAFGWGSPAIVIFVYSMARGLGGT------PEDNRHCW--MNQTNYQN 296
            .:|.:.....|....||:..|||.|.:..          ||      ..::..||  .|.:....
Mouse   229 CLLASTSPRSKPAFWWLVLAGWGLPVLCT----------GTWVGCKLAFEDTECWDLDNSSPCWW 283

  Fly   297 ILMVPVCISMFLNLLFLCNIVRVVLLKLNAPASIQGSCGPSRTVLQAFRATLLLVPLLGL----Q 357
            |:..|:.:|:.:|.....||:.::|.||. ||  ||                      ||    |
Mouse   284 IIKGPIVLSVGVNFGLFLNIICILLRKLE-PA--QG----------------------GLHTRAQ 323

  Fly   358 YILTPFRPAPKHPWENTYEIISAFTASFQGLCVAILFCFC 397
            |            |  .:..:.|.|.... :||.:..|.|
Mouse   324 Y------------W--YHSCVCACTCGCV-VCVCVCVCVC 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh31-R	NP_001260951.1	HRM	65..132	CDD:397086	26/77 (34%)
		7tmB1_NPR_B4_insect-like	139..411	CDD:320388	66/273 (24%)
		TM helix 1	141..166	CDD:320388	9/24 (38%)
		TM helix 2	175..197	CDD:320388	6/21 (29%)
		TM helix 3	214..241	CDD:320388	8/26 (31%)
		TM helix 4	253..273	CDD:320388	6/19 (32%)
		TM helix 5	291..320	CDD:320388	6/28 (21%)
		TM helix 6	339..366	CDD:320388	4/30 (13%)
		TM helix 7	373..398	CDD:320388	6/25 (24%)
Ghrhr	XP_036021736.1	HRM	53..112	CDD:397086	23/68 (34%)
		7tm_GPCRs	126..>325	CDD:475119	59/245 (24%)
		TM helix 1	129..153	CDD:410628	8/23 (35%)
		TM helix 2	162..183	CDD:410628	6/20 (30%)
		TM helix 3	203..225	CDD:410628	6/21 (29%)
		TM helix 4	244..260	CDD:410628	7/25 (28%)
		TM helix 5	278..301	CDD:410628	4/22 (18%)