Protein Alignment Dh31-R and gipr

DIOPT Version :10

• Sequence 1: NP_001260951.1
• Gene: Dh31-R / 36475
• FlyBaseID: FBgn0052843
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: XP_005157796.1
• Gene: gipr / 101885360
• ZFINID: ZDB-GENE-050516-4
• Length: 514
• Species: Danio rerio
• Alignment Length: 496
• Identity: 128/496 - (25%)
• Similarity: 206/496 - (41%)
• Gaps: 108/496 - (21%)

  Fly    28 ESVAESGPDFDALRAACETRLNASGQLAGSGGPGAEAGTHCAGTFDGWLCWPDTAVGTSAYELCP 92
            ::|.::..:::..|:.|..::::.         ...:|..|...||.:.||.|....|:....||
Zfish    24 KTVKDTVQEWNRYRSECILKISSQ---------PTPSGLFCKSMFDMYACWTDGVPNTTVKVPCP 79

  Fly    93 DFITGFDPAR--YAHKECGLDGEWFKHPLT---NKTWSNYTTCVNLEDLNWRHTV---------- 142
            .::...|..|  :..:|||.||:|    ||   :.||.:::.|    :.:.|..:
Zfish    80 WYLPWHDQVRNGFVSRECGPDGQW----LTVNHSSTWRDHSQC----NADGRQQIAQENQMMVLA 136

  Fly   143 --NLISEVGYGTSLLAILLSLAILGYFKSLKCARITLHMNLFASFAANNSLWLVWYLLVMPNSE- 204
              .::..|||..||.::.|:|.||..|:.|:|.|..:|.||||||.......|....|:|.::.
Zfish   137 YFRVMYTVGYSLSLASLSLALIILLIFRKLRCTRNYIHTNLFASFILRAVSILTRDALLMKDAPE 201

  Fly   205 ----------LLHQSPMRCVALHITLHYFLLSNYSWMLCEGFYLHTVLVAAFISEKRLVKWLIAF 259
                      |..|....|....:.:.|.:.:||.|:|.||.|||.:||....||...:......
Zfish   202 FRDNKDVSIVLSDQVMSGCRVAQVLMQYCVGANYYWLLVEGLYLHNLLVLMVFSENSYICVYFFI 266

  Fly   260 GWGSPAIVIFVYSMARGLGGTPEDNRHCWMNQTN--YQNILMVPVCISMFLNLLFLCNIVRVVLL 322
            |||:|.:.:..:.:.|.|    .:|..||....|  |..|:..|:.:::.:|......|:.:::.
Zfish   267 GWGTPVLFVVPWIIVRYL----YENTRCWEINENMAYWWIIRTPILLAILVNFFIFIRIILILIS 327

  Fly   323 KLNAPASIQGSCGPSRTVLQAFR---ATLLLVPLLGLQYILTPFRPAPKHPWE----NTYEIISA 380
            ||.|        ...|.....||   :||.|:||||:..::  |....:...|    |.......
Zfish   328 KLKA--------HQMRYTDYKFRLAKSTLTLIPLLGIHEVV--FAVMTEEQTEGVLRNVNLFFEL 382

  Fly   381 FTASFQGLCVAILFCFCNGEVIAQMKRKWR-----MMCFSNRPRTNSYTATQVSFVRCGPPLPGE 440
            |..||||..||||:||.|.||.:::|:||:     :....::..|.|.|
Zfish   383 FFNSFQGFLVAILYCFVNKEVQSEIKKKWQRWKLGISILDDQRNTGSNT---------------- 431

  Fly   441 EKVXLKDMSAKRRASAGPQ-HHQPH-------HQSHQLSTD 473
                       :....||| ||.|.       ....|||:|
Zfish   432 -----------QPVGTGPQCHHDPACSPECPLDSGSQLSSD 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh31-R	NP_001260951.1	HRM	65..132	CDD:397086	23/71 (32%)
		7tmB1_NPR_B4_insect-like	139..411	CDD:320388	89/308 (29%)
		TM helix 1	141..166	CDD:320388	9/36 (25%)
		TM helix 2	175..197	CDD:320388	8/21 (38%)
		TM helix 3	214..241	CDD:320388	10/26 (38%)
		TM helix 4	253..273	CDD:320388	4/19 (21%)
		TM helix 5	291..320	CDD:320388	6/30 (20%)
		TM helix 6	339..366	CDD:320388	10/29 (34%)
		TM helix 7	373..398	CDD:320388	12/24 (50%)
gipr	XP_005157796.1	HRM	52..121	CDD:397086	23/76 (30%)
		7tmB1_GlucagonR-like	135..413	CDD:341353	88/291 (30%)
		TM helix 1	137..162	CDD:341353	9/24 (38%)
		TM helix 2	171..193	CDD:341353	8/21 (38%)
		TM helix 3	221..248	CDD:341353	10/26 (38%)
		TM helix 4	260..280	CDD:341353	4/19 (21%)
		TM helix 5	296..325	CDD:341353	6/28 (21%)
		TM helix 6	339..366	CDD:341353	10/28 (36%)
		TM helix 7	375..400	CDD:341353	12/24 (50%)