Protein Alignment Dh31-R and vipr1

DIOPT Version :10

• Sequence 1: NP_001260951.1
• Gene: Dh31-R / 36475
• FlyBaseID: FBgn0052843
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: XP_031759879.1
• Gene: vipr1 / 100497291
• XenbaseID: XB-GENE-5991267
• Length: 444
• Species: Xenopus tropicalis
• Alignment Length: 419
• Identity: 122/419 - (29%)
• Similarity: 194/419 - (46%)
• Gaps: 78/419 - (18%)

  Fly    62 AEAGTH---CAGTFDGWLCWPDTAVGTSAYELCPDFI-------------------TGFDPARYA 104
            :||..|   |..::|...||...:||......|||:.                   |...||.||
 Frog    44 SEAENHTLGCKASWDNITCWRSASVGEVVVMPCPDYFGFFSNVQGNVSRNCTEHGWTDMFPAPYA 108

  Fly   105 HKECGLDGEWFKHPLTNKTWSNYTTCVNLEDLNWRHTVNLISEVGYGTSLLAILLSLAILGYFKS 169
             ..||.|        ||.|.:..|...::....:        .:|:..||:::..::.||.:|:.
 Frog   109 -IACGFD--------TNNTTNGQTEFFSMIKTGY--------TIGHSVSLISLTAAMIILFFFRK 156

  Fly   170 LKCARITLHMNLFASFAANNSLWLVWYLLVMPNSELLH--QSPMRCVALHITLHYFLLSNYSWML 232
            |.|.|..:||:||.||........|..:::..:.|..|  ...:.|.|..:...|.:::|:.|:|
 Frog   157 LHCTRNYIHMHLFMSFIMRAIAVFVKDIVLFESGEFDHCFVGSVGCKAAMVFFQYCIMANFFWLL 221

  Fly   233 CEGFYLHTVLVAAFISEKRLVKWLIAFGWGSPAIVIFVYSMARGLGGTPEDNRHCWMN-QTNYQN 296
            .||.||||:||.:|.|||:...|.|..|||||.:.|..:::.|    ...|:..||.. ::.:..
 Frog   222 VEGLYLHTLLVISFFSEKKYFWWYILIGWGSPTVFITAWTVTR----IHFDDSGCWDTIESPFWW 282

  Fly   297 ILMVPVCISMFLNLLFLCNIVRVVLLKLNAPASIQGSCGPSRT--VLQAFRATLLLVPLLGLQYI 359
            |:..|:.||:.:|.:|...|:|:::.||::|     ..|.:..  ..:..::||||:||.|:.||
 Frog   283 IIRAPILISISVNFIFFICIIRILVQKLHSP-----DVGRNENSQYTRLAKSTLLLIPLFGVHYI 342

  Fly   360 LTPFRPAPKHPWENTYE-----IISAFTASFQGLCVAILFCFCNGEVIAQMKRKWRMMCFS---- 415
            :..|.|       :.::     |:.....||||..||||:||.||||..::|||||.....
 Frog   343 MFAFFP-------DNFKVEIKLIVELVLGSFQGFVVAILYCFLNGEVQGELKRKWRRWHLERFLG 400

  Fly   416 -----NRPRTNS---YTATQVSFV-RCGP 435
                 :.|...|   ..:||:|.: :|.|
 Frog   401 SDMKYHHPSLGSNGTNFSTQISMLTKCSP 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh31-R	NP_001260951.1	HRM	65..132	CDD:397086	22/88 (25%)
		7tmB1_NPR_B4_insect-like	139..411	CDD:320388	90/281 (32%)
		TM helix 1	141..166	CDD:320388	5/24 (21%)
		TM helix 2	175..197	CDD:320388	7/21 (33%)
		TM helix 3	214..241	CDD:320388	10/26 (38%)
		TM helix 4	253..273	CDD:320388	8/19 (42%)
		TM helix 5	291..320	CDD:320388	8/28 (29%)
		TM helix 6	339..366	CDD:320388	10/28 (36%)
		TM helix 7	373..398	CDD:320388	11/29 (38%)
vipr1	XP_031759879.1	HormR	50..120	CDD:214468	20/78 (26%)
		7tm_GPCRs	126..392	CDD:475119	90/289 (31%)
		TM helix 1	129..153	CDD:320397	5/31 (16%)
		TM helix 2	162..183	CDD:320397	7/20 (35%)
		TM helix 3	203..225	CDD:320397	6/21 (29%)
		TM helix 4	244..260	CDD:320397	8/15 (53%)
		TM helix 5	277..300	CDD:320397	6/22 (27%)
		TM helix 6	327..349	CDD:320397	11/28 (39%)
		TM helix 7	354..379	CDD:320397	11/24 (46%)