DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dh31-R and LOC100492996

DIOPT Version :9

Sequence 1:	NP_001260951.1	Gene:	Dh31-R / 36475	FlyBaseID:	FBgn0052843	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	XP_002935751.2	Gene:	LOC100492996 / 100492996	-ID:	-	Length:	422	Species:	Xenopus tropicalis

Alignment Length:	407	Identity:	122/407 - (29%)
Similarity:	199/407 - (48%)	Gaps:	51/407 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 AACETRL---NASGQLAGSGGPGAEAGTHCAGTFDGWLCWPDTAVGTSAYELCPDFITGFDPARY 103
            |.|..|:   |||.:....||        |...:||..||...::|.:....||:.:..|..::.
Frog    44 AQCYERIRVENASSRNFTHGG--------CNMEWDGVNCWRAASIGQTVTVSCPESLQMFLNSKV 100

  Fly   104 A-HKECGLDGEWFKH--PLTNKTWSNYTTCV------NLEDLNWRHTVNLISEVGYGTSLLAILL 159
            . .:.|..|| |..|  |.       |..|:      ..|...:.|||.::...||..||.|::.
Frog   101 VISRNCTEDG-WTPHSPPY-------YKACIFSGTNETEEKREYFHTVKILYTCGYAASLTALVT 157

  Fly   160 SLAILGYFKSLKCARITLHMNLFASFAANNSLWLVWYLLVMPNSELLH--QSPMRCVALHITLHY 222
            :::|...|:.|.|.|..:|:|||.||........:...::..:.::.|  .|.:.|.|..:...|
Frog   158 AISIFSLFRKLHCPRNFIHVNLFVSFILRGIAVFIKDAVLFADEDVDHCTMSTVGCKAAVVFFQY 222

  Fly   223 FLLSNYSWMLCEGFYLHTVLVAAFISEKRLVKWLIAFGWGSPAIVIFVYSMARGLGGTPEDNRHC 287
            .:|:|:||:|.||.||||:|...|..:::...|.|..|||:||:.|.|:...|    ...||..|
Frog   223 SVLANFSWLLVEGMYLHTLLTLTFTYQRKYFWWYIVIGWGAPALTISVWIKTR----IQFDNTGC 283

  Fly   288 WMN-QTNYQNILMVPVCISMFLNLLFLCNIVRVVLLKLNAPASIQGSCGPSRTVLQAFRATLLLV 351
            |.: ::.|..|:..|:.:::|:|.:...|::|:::.|:..|   ..|....:..::..::||||:
Frog   284 WDDYESIYWWIIKTPILLAIFINFIIFLNVIRILIQKIRCP---DISKNYKQQYMRLAKSTLLLI 345

  Fly   352 PLLGLQYILTPFRPAPKH--PWENTY-EIISAFTASFQGLCVAILFCFCNGEVIAQMKR---KWR 410
            ||.|:.|::  |...|:|  .|...| |::   ..|.||..||:|:||.||||.|:::|   ||:
Frog   346 PLFGVHYVI--FALFPEHIGIWARMYFELV---LGSNQGFIVALLYCFLNGEVQAEIQRHWGKWQ 405

  Fly   411 MMCFSN--RPRTNSYTA 425
            ....||  ...|..:||
Frog   406 SSLESNVFNLVTQDFTA 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dh31-R	NP_001260951.1	HRM	65..132	CDD:280888	17/75 (23%)
Dh31-R	NP_001260951.1	7tm_4	140..390	CDD:304433	78/255 (31%)
LOC100492996	XP_002935751.2	HRM	62..124	CDD:367186	19/77 (25%)
		7tmB1_GHRHR2	137..403	CDD:320399	89/277 (32%)
		TM helix 1	139..164	CDD:320399	8/24 (33%)
		TM helix 2	173..195	CDD:320399	6/21 (29%)
		TM helix 3	214..241	CDD:320399	12/26 (46%)
		TM helix 4	253..273	CDD:320399	9/19 (47%)
		TM helix 5	288..317	CDD:320399	7/28 (25%)
		TM helix 6	333..360	CDD:320399	9/28 (32%)
		TM helix 7	365..390	CDD:320399	11/27 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X66
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000