Protein Alignment Dh31-R and pth1r

DIOPT Version :9

• Sequence 1: NP_001260951.1
• Gene: Dh31-R / 36475
• FlyBaseID: FBgn0052843
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: XP_002939411.2
• Gene: pth1r / 100492020
• XenbaseID: XB-GENE-957445
• Length: 540
• Species: Xenopus tropicalis
• Alignment Length: 553
• Identity: 156/553 - (28%)
• Similarity: 241/553 - (43%)
• Gaps: 130/553 - (23%)

  Fly    41 RAACETRLNASGQLAGSGGPGAEAGTHCAGTFDGWLCWPDTAVGTSAYELCPDFITGFDPARYAH 105
            :|.||..|::|...|..|        .|...:||.:|||:...|.:....||::|..|:...:|:
 Frog    46 KALCEKLLSSSASKAHDG--------LCLPEWDGVVCWPEGLPGNTVSISCPEYIQDFNHKGHAY 102

  Fly   106 KECGLDGEWFKHPLTNKTWSNYTTCVN--LEDLNWRHTVN---LISEVGYGTSLLAILLSLAILG 165
            :.|.::|.|...|..|:||:|||.|..  ..:...|...:   ||..|||..||.::.:::.|||
 Frog   103 RRCDMNGSWELVPGNNRTWANYTECAKYLFNETKEREVFDRLYLIYTVGYSISLGSLTVAVLILG 167

  Fly   166 YFKSLKCARITLHMNLFASFAAN-NSLWLVWYLL----VMPNSELLHQSPMR------------- 212
            ||:.|.|.|..:||:||.||... .|:::...:|    .:..:||:.:..::
 Frog   168 YFRRLHCTRNYIHMHLFISFMLRAGSIFVKDAVLYSGSALEETELISEEDLKFITEIPPADKMQF 232

  Fly   213 --CVALHITLHYFLLSNYSWMLCEGFYLHTVLVAAFISEKRLVKWLIAFGWGSPAIVIFVYSMAR 275
              |..:.....|||.:||.|:|.||.|||:::..||||:|:.:.....||||.|||.:.:::..|
 Frog   233 VGCKVVVTFFLYFLATNYYWILVEGLYLHSLIFMAFISDKKYLWGFTLFGWGVPAIFVLIWARER 297

  Fly   276 GLGGTPEDNRHCWMNQTNYQN-ILMVPVCISMFLNLLFLCNIVRVVLLKL---NAPASIQGSCGP 336
               .|..|. .||.....|.. |:.||:..::.:|.....|||||:..||   ||     |.|..
 Frog   298 ---ATVADT-GCWDLSAGYLKWIVQVPILAAIMVNFGLFINIVRVLATKLRETNA-----GRCDT 353

  Fly   337 SRTVLQAFRATLLLVPLLGLQYIL---TPFRPAPKHPW--ENTYEIISAFTASFQGLCVAILFCF 396
            .:...:..::||:|:||.|:.||:   .|:.......|  :..||::  |. ||||..|||::||
 Frog   354 RQQYRKLLKSTLVLMPLFGVHYIVFMAFPYTEVSGILWQVQMHYELL--FN-SFQGFFVAIIYCF 415

  Fly   397 CNGEVIAQMKRKWR----MMCFSNRPRTNSYTATQVSFVRCGP---------------------- 435
            |||||.|::|:.|.    .:.|..:.|:.|.|.:.      ||
 Frog   416 CNGEVQAEIKKSWSRWTLALDFKRKARSGSTTYSY------GPMVSHTSITNVTTRGTLALHLNT 474

  Fly   436 -----------PLPGEEKVXLKDMSAKRRASAGPQHHQPHHQSHQLSTDQQRARSQSLASSSSFL 489
                       .|||..|..  .:|.....|:||.         |.:.|::......|
 Frog   475 RLVSTALNGHRNLPGYVKNG--SLSENSIPSSGPD---------QYNKDEEYINGSGL------- 521

  Fly   490 EGWRDRMPFLKRRQTIDHSRQSQPLMEEGGETV 522
                           .|..|.:..::||..|||
 Frog   522 ---------------YDGERPTPAVVEEERETV 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh31-R	NP_001260951.1	HRM	65..132	CDD:280888	23/66 (35%)
		7tm_4	140..390	CDD:304433	88/281 (31%)
pth1r	XP_002939411.2	HRM	65..127	CDD:367186	22/61 (36%)
		7tmB1_PTH1R	141..430	CDD:320650	101/300 (34%)
		TM helix 1	143..168	CDD:320650	9/24 (38%)
		TM helix 2	177..199	CDD:320650	7/21 (33%)
		TM helix 3	236..263	CDD:320650	12/26 (46%)
		TM helix 4	275..295	CDD:320650	7/19 (37%)
		TM helix 5	310..339	CDD:320650	9/28 (32%)
		TM helix 6	356..383	CDD:320650	8/26 (31%)
		TM helix 7	392..417	CDD:320650	12/27 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X66
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000