Protein Alignment Dh31-R and calcr

DIOPT Version :10

• Sequence 1: NP_001260951.1
• Gene: Dh31-R / 36475
• FlyBaseID: FBgn0052843
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: XP_002934645.2
• Gene: calcr / 100491101
• XenbaseID: XB-GENE-952135
• Length: 478
• Species: Xenopus tropicalis
• Alignment Length: 386
• Identity: 151/386 - (39%)
• Similarity: 223/386 - (57%)
• Gaps: 27/386 - (6%)

  Fly    60 PGAEAGTHCAGTFDGWLCWPDTAVGTSAYELCPDFITGFDPARYAHKECGLDGEWFKHPLTNKTW 124
            |.:::|.:|..|:||||||.||..|.:..:.|||:...|||...|.|.|..:|.||:||.:|:||
 Frog    72 PYSKSGLYCNRTWDGWLCWDDTPAGINVTQNCPDYFPDFDPTERASKYCDENGNWFQHPESNRTW 136

  Fly   125 SNYTTCVNL--EDLNWRHTVNLISEVGYGTSLLAILLSLAILGYFKSLKCARITLHMNLFASFAA 187
            ||||.|.:.  |.|...:.:..::.||:..|::::::||.|..|||||.|.|||||.|||.|:..
 Frog   137 SNYTLCNSFTSEKLKMAYILYYMAIVGHALSIVSLMISLGIFFYFKSLSCQRITLHKNLFTSYVL 201

  Fly   188 NNSLWLVWYLLVMPNSELLHQSPMRCVALHITLHYFLLSNYSWMLCEGFYLHTVLVAAFISEKRL 252
            |:...:|....|:|:::|:...|:.|..|.....|.|..||.||||||.||||::|.|..:|::.
 Frog   202 NSVFTIVHLTAVVPDTDLVRSDPVSCKVLQFFSQYMLGCNYFWMLCEGIYLHTLIVVAVFAEEQH 266

  Fly   253 VKWLIAFGWGSPAIVIFVYSMARGLGGTPEDNRHCWMN-QTNYQNILMVPVCISMFLNLLFLCNI 316
            :.|....|||.|.:...:::.||    |...|.:|||: :|:...|:..|:..::.:||.||.||
 Frog   267 LHWYYLLGWGFPLVPASIHAFAR----TKYFNDNCWMSVETHLLYIVHGPIMAALLVNLFFLLNI 327

  Fly   317 VRVVLLKLNAPASIQGSCGPSRTVLQAFRATLLLVPLLGLQYILTPFRPAPKHPWENTYEIISAF 381
            |.|::.||......:     |...::|.||||:||||||:|:::.|:||..:...| .|:.|...
 Frog   328 VLVLVTKLRDTHRAE-----SNMYMKAVRATLILVPLLGIQFVIFPWRPDTRLAGE-IYDYIMNI 386

  Fly   382 TASFQGLCVAILFCFCNGEVIAQMKRKW-----------RMMCFSNRPRTNSYTATQVSFV 431
            ...:|||.||.:|||.||||...:||:|           |..|   ..|:.|||||.::.|
 Frog   387 LMHYQGLLVATIFCFFNGEVQGALKRQWMQYKTQWGQRRREHC---SMRSTSYTATSITEV 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh31-R	NP_001260951.1	HRM	65..132	CDD:397086	34/66 (52%)
		7tmB1_NPR_B4_insect-like	139..411	CDD:320388	105/283 (37%)
		TM helix 1	141..166	CDD:320388	6/24 (25%)
		TM helix 2	175..197	CDD:320388	10/21 (48%)
		TM helix 3	214..241	CDD:320388	14/26 (54%)
		TM helix 4	253..273	CDD:320388	5/19 (26%)
		TM helix 5	291..320	CDD:320388	10/28 (36%)
		TM helix 6	339..366	CDD:320388	14/26 (54%)
		TM helix 7	373..398	CDD:320388	10/24 (42%)
calcr	XP_002934645.2	HRM	77..145	CDD:397086	34/67 (51%)
		7tmB1_calcitonin_R	153..426	CDD:341343	105/282 (37%)
		TM helix 1	155..180	CDD:341343	6/24 (25%)
		TM helix 2	189..211	CDD:341343	10/21 (48%)
		TM helix 3	228..255	CDD:341343	14/26 (54%)
		TM helix 4	267..287	CDD:341343	5/19 (26%)
		TM helix 5	302..331	CDD:341343	10/28 (36%)
		TM helix 6	345..372	CDD:341343	14/26 (54%)
		TM helix 7	378..403	CDD:341343	11/25 (44%)