Protein Alignment CG42319 and PDZD7

DIOPT Version :9

• Sequence 1: NP_001137648.1
• Gene: CG42319 / 36473
• FlyBaseID: FBgn0259219
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_001182192.1
• Gene: PDZD7 / 79955
• HGNCID: 26257
• Length: 1033
• Species: Homo sapiens
• Alignment Length: 497
• Identity: 104/497 - (20%)
• Similarity: 163/497 - (32%)
• Gaps: 173/497 - (34%)

  Fly    38 VDSDAYATKDDS--------------RWGFLITGGAEFHMPLTVFQVTPNGLADKAGIRLGDIIL 88
            ::|...|..|:|              |.||.:.||:|..:.:.|.:|.....|::||:.:||.|.
Human    70 INSPIEANSDESDIIHSVRVEKSPAGRLGFSVRGGSEHGLGIFVSKVEEGSSAERAGLCVGDKIT 134

  Fly    89 EINEEDASQLTLSQAHEKINSTPKKIHFLLRNMEEDDPMGQFEAGEEKSIVMRVPKPLPPPSGRI 153
            |:|.......|:..| .|:.::..::|.::|.|.                  |||        .|
Human   135 EVNGLSLESTTMGSA-VKVLTSSSRLHMMVRRMG------------------RVP--------GI 172

  Fly   154 RASSIEMRLLE-MQRKLSAIAEIPKILCSTLATVSQNFGRMSESEVDEDDVGEEEAYVQRKFSYD 217
            :.|..:...:: :.|:|                |.:..|........||.|   ...|....:.|
Human   173 KFSKEKTTWVDVVNRRL----------------VVEKCGSTPSDTSSEDGV---RRIVHLYTTSD 218

  Fly   218 EDALDFELRNGEQAG---------------DTDSDEEDLVL----VREED---AEDVDVPKGAKQ 260
            :..|.|.:|.|::.|               :......|.||    ||.:|   ::.|:|.||...
Human   219 DFCLGFNIRGGKEFGLGIYVSKVDHGGLAEENGIKVGDQVLAANGVRFDDISHSQAVEVLKGQTH 283

  Fly   261 SKL----------------------------LKDVTPESDYASEANYPANEA---SDDTESD--- 291
            ..|                            |:.::|.|:.:|..:..|:.|   |....||
Human   284 IMLTIKETGRYPAYKEMVSEYCWLDRLSNGVLQQLSPASESSSSVSSCASSAPYSSGSLPSDRMD 348

  Fly   292 ---DEDEPGSTVYFMKLPAAAAEDTYSSTEDEDDSDFLNTTYTW-NLRNVPKLRINDAEAEGELT 352
               .::||||     :.|.....||...||    .|......|| ::|....||.....::|.
Human   349 ICLGQEEPGS-----RGPGWGRADTAMQTE----PDAGGRVETWCSVRPTVILRDTAIRSDGP-- 402

  Fly   353 LGHQAREVPQQEQPQEKQPCL----EPEPP------------------KVRPATPTPKAPPQESA 395
              |..|.:........|...|    .|.||                  |.:..:|..|...|.|.
Human   403 --HPGRRLDSALSESPKTALLLALSRPRPPITRSQSYLTLWEEKQQRKKEKSGSPGEKGALQRSK 465

  Fly   396 -------EGQTQKLLFR--------LD--KLERSWPWADREK 420
                   :|..|..|.|        ||  .|.:::|..|.||
Human   466 TLMNLFFKGGRQGRLARDGRREAWTLDSGSLAKTYPRLDIEK 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42319	NP_001137648.1	PDZ_signaling	45..119	CDD:238492	22/87 (25%)
PDZD7	NP_001182192.1	PDZ_signaling	84..164	CDD:238492	20/80 (25%)
		PDZ_signaling	209..289	CDD:238492	18/79 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	323..380		16/65 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	444..464		4/19 (21%)
		HN_PDZD7_like	554..630	CDD:259824
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	754..864
		PDZ_signaling	860..948	CDD:238492
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	943..1033

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900