DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42319 and Pdzk1

DIOPT Version :9

Sequence 1:	NP_001137648.1	Gene:	CG42319 / 36473	FlyBaseID:	FBgn0259219	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_113900.1	Gene:	Pdzk1 / 65144	RGDID:	70924	Length:	523	Species:	Rattus norvegicus

Alignment Length:	411	Identity:	80/411 - (19%)
Similarity:	143/411 - (34%)	Gaps:	127/411 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 PESKSKAPIIKVSCGIGDTDGYPAFDVDSDAYATKDDSRWGF-LITGGAEFHMPLTVFQVTPNGL 75
            |....|.|.:.::.|: :|...|..     .|..|:.:.:|| |.|...:..:.||  .:||.|:
  Rat   112 PALNEKKPDLGMNGGV-ETCAQPRL-----CYLVKEGNSFGFSLKTIQGKKGVFLT--DITPQGV 168

  Fly    76 ADKAGIRLGDIILEINEEDASQLTLSQAHEKINSTPKKIHFLL-------RNMEEDDPMGQ---- 129
            |.|||:...|.::|:|.|:....:..:..||:..:..:|.|||       .:.|:..|..:
  Rat   169 AMKAGVLADDHLIEVNGENVENASHEEVVEKVTKSGSRIMFLLVDKETARCHSEQKTPFKRETAS 233

  Fly   130 -----------------------FEAG-EEKSIVMRVPKPLPPPSG----------RIRASSIEM 160
                                   ..|| |:|..:::..:|..|...          .:...|:|.
  Rat   234 LKLLPHQPRVVVIKKGSNGYGFYLRAGPEQKGQIIKDIEPGSPAEAAGLKNNDLVVAVNGESVEA 298

  Fly   161 ----RLLEMQR----------------KLSAIAEI-PKILCSTLATVSQNF--GRMSES------ 196
                .::||.|                ::.::|.. |.:.|.     ||..  |.:.|:
  Rat   299 LDHDSVVEMIRNGGDQTTLLVLDKEADRIYSLARFSPLLYCQ-----SQELPNGSVKEAPAPISA 358

  Fly   197 ------EVDEDDVGEEEAYVQRKFSYDEDALDFEL-----------RNGEQAGDTDS---DEEDL 241
                  ....:|||:.:..:.|... ::|:..|.|           :..:|.|..|.   :.||:
  Rat   359 PLEAPGSATTEDVGDHKPKLCRLIK-EDDSYGFHLNAIRGQPGSFVKEVQQGGPADKAGLENEDI 422

  Fly   242 VL-VREEDAEDVDVPKGAKQSK-------LLKDVTPESDYASEANYPANEASDDTESDDEDEPGS 298
            :: |..|:.:|....:..::.|       ||........|......|...:..|......||.|.
  Rat   423 IIEVNGENVQDEPYDRVVERIKSSGEHVTLLVCGKVAYSYFQAKKIPILSSLADPLVAGPDEKGE 487

  Fly   299 TVYFMKLPAAAAEDTYSSTED 319
            |.:          |:..||:|
  Rat   488 TEH----------DSAESTKD 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42319	NP_001137648.1	PDZ_signaling	45..119	CDD:238492	24/81 (30%)
Pdzk1	NP_113900.1	PDZ_signaling	7..87	CDD:238492
		PDZ	132..212	CDD:214570	25/86 (29%)
		PDZ_signaling	242..320	CDD:238492	11/77 (14%)
		PDZ	375..455	CDD:214570	15/80 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	479..523		8/30 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900