Protein Alignment CG42319 and Pdzd2

DIOPT Version :9

• Sequence 1: NP_001137648.1
• Gene: CG42319 / 36473
• FlyBaseID: FBgn0259219
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: XP_038959013.1
• Gene: Pdzd2 / 65034
• RGDID: 619958
• Length: 2818
• Species: Rattus norvegicus
• Alignment Length: 552
• Identity: 109/552 - (19%)
• Similarity: 161/552 - (29%)
• Gaps: 218/552 - (39%)

  Fly    52 GFLITGGAEF---HMPLTVFQVTPNGLADKAG-IRLGDIILEINEEDASQLTLSQA--------- 103
            ||.|.||.:.   .|.:.|..:.|||.|.:.| ::.||.||::|......||..:|
  Rat   599 GFSIAGGRDCIRGQMGIFVKTIFPNGSAAEDGRLKEGDEILDVNGIPIKGLTFQEAIHTFKQIRS 663

  Fly   104 -----------------------HEKINSTPKKIHFLLRN--------MEE--DDPMGQFEAGEE 135
                                   |...:|:|.   |...:        .||  ...:|:...|.:
  Rat   664 GLFVLTVRTKLLSPSLTPCSTPTHMSRSSSPS---FNTNSGGTPAGGGQEEGGSSSLGRKAPGPK 725

  Fly   136 KSIVMRVPKPLPP----------------PSGRIRASSIEMRLLEMQRKLS-------------- 170
            ..|||.|.....|                |.|....|.....:.:|:..||
  Rat   726 DRIVMEVTLNKEPRVGLGIGACCLALENSPPGIYIHSLAPGSVAKMESNLSRGDQILEVNSVNVR 790

  Fly   171 --AIAEIPKIL--CSTLATVSQNFGR-----MSESEVDEDDVGEEEAYVQRKFSYDEDALDFELR 226
              |::::..||  |.. ..|....||     :||.|:||  |.....|.:.:.:.....|...|:
  Rat   791 HAALSKVHAILSKCPP-GPVRLVIGRHPNPKVSEQEMDE--VIARSTYQESREANSSPGLGTPLK 852

  Fly   227 NGEQAGDTDSDEEDLVLVREEDAEDVDVPKGAKQSKLLKDVTPESDYASEANYPANEASDD---T 288
            :                           |..||:..||.    ||:.:....:....:..|   .
  Rat   853 S---------------------------PSLAKKDSLLS----ESELSQYFVHDGQGSLSDFVVA 886

  Fly   289 ESDDEDEPGSTVYFMK----LPAAAAEDT------------------------------------ 313
            .|:|||.|||.....:    ||..:|...
  Rat   887 GSEDEDHPGSGYETSEDGSLLPVPSAHKARANSLVTLGSQRTSGLLHKQVTVARQASLPGSPQVL 951

  Fly   314 ------------YSSTEDEDDSDFLNTTYTWNLRNV---PKLRINDAEAEGELTLGHQAREVPQQ 363
                        |.|....||.||.......:|..|   |...:.:.:....||...::.:|.:|
  Rat   952 RNPLLRQRRVRCYDSNGGSDDEDFDGEGDCISLPGVLPGPGKPLVEDDTRPALTTSSKSIDVNKQ 1016

  Fly   364 EQ----PQEKQPCLEP------------------EPPKVR--PAT-PTPKAPPQESAEGQTQKLL 403
            |:    |...:.|..|                  .||||.  |.: .|||..|:.|...:...
  Rat  1017 EERLQKPLVSKACSVPLLGSSLDSEHSILNGTGGTPPKVASLPGSGETPKNGPRGSGRKEMSG-- 1079

  Fly   404 FRLDKLERSWPWADREKIIYKQSTCHLVPRKP 435
                  .||.|     |:.|:..|....||.|
  Rat  1080 ------SRSSP-----KLEYRVPTDTQSPRSP 1100

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42319	NP_001137648.1	PDZ_signaling	45..119	CDD:238492	24/102 (24%)
Pdzd2	XP_038959013.1	PDZ_signaling	335..416	CDD:238492
		PDZ_signaling	590..671	CDD:238492	20/71 (28%)
		PDZ_signaling	729..813	CDD:238492	15/84 (18%)
		PHA03247	<985..1446	CDD:223021	29/129 (22%)
		PDZ_signaling	2603..2677	CDD:238492
		PDZ_signaling	2731..2813	CDD:238492

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900