DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42319 and pdlim4

DIOPT Version :9

Sequence 1:	NP_001137648.1	Gene:	CG42319 / 36473	FlyBaseID:	FBgn0259219	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001036161.1	Gene:	pdlim4 / 569404	ZFINID:	ZDB-GENE-070308-5	Length:	349	Species:	Danio rerio

Alignment Length:	245	Identity:	58/245 - (23%)
Similarity:	92/245 - (37%)	Gaps:	47/245 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 SRWGFLITGGAEFHMPLTVFQVTPNGLADKAGIRLGDIILEINEEDASQLTLSQAHEKINS-TPK 112
            |.|||.:.||.:|..|||:.::||...|.::.:..||.||.||.|....:|..:|..:|.: |.:
Zfish    11 SPWGFRLVGGRDFSTPLTISRITPASKAAQSNLSPGDTILAINGESTESMTHMEAQNRIKACTDQ 75

  Fly   113 KIHFLLRNMEEDDPMGQFEAG--------EEKSIVMR-----------VPKPLPPPSGRIRASSI 158
            .:..:.|:.:...|.|..|..        |..|...|           .|.|..|.:|.:..::.
Zfish    76 LVLAICRSGKAWSPTGMEELKTSPFSPTLESDSQTFRPISSGYSPTPKSPSPKSPITGAVPYNNG 140

  Fly   159 EMRLLEMQRKLSAIAEIPKILCSTLATVSQNFGRMS-ESEVDEDDVGEEEAYVQRKFSYDEDALD 222
            ..|               .:..:.....|.|.|..: ..::....:|...:     ||.:.....
Zfish   141 GSR---------------PVYNNPAGLYSHNNGNGALPKQMSGLSLGSPHS-----FSPEPPVNS 185

  Fly   223 FELRNGEQAGDTDSDEEDLVLVREEDAEDVDVPKGAKQSKLLKDVTPESD 272
            ...|||   .||.||...::|..|   |.|..||.:...|.|:.:....|
Zfish   186 SGNRNG---FDTQSDVYRMLLDYE---EPVSAPKQSGSFKYLQGILEAED 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42319	NP_001137648.1	PDZ_signaling	45..119	CDD:238492	24/70 (34%)
pdlim4	NP_001036161.1	PDZ_signaling	3..78	CDD:238492	24/66 (36%)
		DUF4749	146..233	CDD:292558	22/95 (23%)
		LIM_RIL	274..326	CDD:188835
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24214
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100