DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42319 and lnx1

DIOPT Version :9

Sequence 1:	NP_001137648.1	Gene:	CG42319 / 36473	FlyBaseID:	FBgn0259219	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	XP_005160562.1	Gene:	lnx1 / 561226	ZFINID:	ZDB-GENE-030131-9439	Length:	769	Species:	Danio rerio

Alignment Length:	181	Identity:	44/181 - (24%)
Similarity:	72/181 - (39%)	Gaps:	41/181 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 GFLITGGAE---FHMPLTVFQVTPNGLADKAG-IRLGDIILEINEEDASQLTLSQAHEKINSTPK 112
            |..:.||..   :.:|:.|..|.|||:..:.| ||.|||:|.:|..|.:.:|.|:|...:.:|..
Zfish   550 GMTVAGGMSSRGWDLPVYVTNVDPNGVVGQEGSIRKGDILLNVNGVDLTGVTRSEAVANLKNTSS 614

  Fly   113 KIHFLLRNMEEDDPMGQFEAGEEKSIVMRVP----------KP----LPPPSGRIRASSIEMRLL 163
            .:  :|:.:|...|       .|.|:....|          .|    ||||:...  :.:.:..|
Zfish   615 PV--VLQVLEMRPP-------NESSLDCMPPLHSPCALSPSSPGDVKLPPPNDDY--APLWVSWL 668

  Fly   164 EMQRKLSAIAEIPKILCSTLATVSQNFGRMSESEVDEDDVGEEEAYVQRKF 214
            ::.|.|        ..|..:.......|.:..|.|.    |:||....:.|
Zfish   669 QLPRHL--------YCCKDIVLRRSTSGSLGFSIVG----GQEELNCNQSF 707

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42319	NP_001137648.1	PDZ_signaling	45..119	CDD:238492	22/70 (31%)
lnx1	XP_005160562.1	RING	57..93	CDD:214546
		PDZ_signaling	297..381	CDD:238492
		PDZ_signaling	411..491	CDD:238492
		PDZ_signaling	536..621	CDD:238492	23/72 (32%)
		DegQ	<548..621	CDD:223343	23/72 (32%)
		PDZ_signaling	678..762	CDD:238492	7/34 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900