DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42319 and grid2ipb

DIOPT Version :9

Sequence 1:	NP_001137648.1	Gene:	CG42319 / 36473	FlyBaseID:	FBgn0259219	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	XP_009304908.1	Gene:	grid2ipb / 559717	ZFINID:	ZDB-GENE-040724-161	Length:	1383	Species:	Danio rerio

Alignment Length:	426	Identity:	83/426 - (19%)
Similarity:	149/426 - (34%)	Gaps:	93/426 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 WGFLITGGAEFHMPLTVFQVTPNGLADKAGIRLGDIILEINEEDASQLTLSQAHEKINSTPKKIH 115
            :||.:.|    |.|:.:..|.|...|:..|::.||.||.:|..|....    :|||:.|..:...
Zfish   346 FGFTLRG----HAPVWIDSVMPGSPAEACGLKTGDRILFLNGLDMRNC----SHEKVVSMLQGSG 402

  Fly   116 FLLRNMEEDDPMGQFEAGEEKSIVMRVPK-------------PLPPPSGRIRASSIEMR---LLE 164
            .:...:.|:.|:...::..|.......|:             .:.|||.|:...:...:   ||.
Zfish   403 AMPSLVVEEGPVDYPQSDSEPEETPSAPRSRSPALSSLQWVAEILPPSIRVHGRTFSQQLEHLLT 467

  Fly   165 MQRKLSAIAEIPKILCSTLATVSQNFGRMSESEVDEDDVGEEEA------YVQRKFSYDEDA--- 220
            :|.:.:        :|..|.|..|: ..:....||...|.:..|      ::.:..:|:|..
Zfish   468 LQERYT--------ICKALETFFQH-RNVDTLIVDVFPVLDTPAKQLIWQFIYQLLTYEEQEHCK 523

  Fly   221 ------LDFELRNGEQAGDTDSDEEDLVL--------VREEDAEDVDVPKGAKQSKLLKDVTPES 271
                  |.|:....|...:|......:.:        |||..::|..:............||||.
Zfish   524 TKIARFLGFKSAEPEVGAETHRRSSSMRVSGTSHKNTVRERSSDDCIIGTHLGMGTFTDPVTPEE 588

  Fly   272 DYASE-ANYPANEASDDTESDDEDEPGSTVYFMK---------LPAAAA-----EDTYSSTEDED 321
            ....: .::|  |:.|.:...........||.:|         .|.||.     .:||:.:
Zfish   589 RQCGDGTSFP--ESPDLSHMTGVYTELGNVYPVKSSQSLQSHSSPRAAGMGLAESNTYTQS---- 647

  Fly   322 DSDFLNTTYTWNLRNVPKLRINDAEAEGELTLGHQAREVPQQEQPQEKQPCLEPEPPKVRPATPT 386
               |.::| ..|.::...|...|:....:.....|....|..   .:..|.:..:.|   ||:|.
Zfish   648 ---FTHST-AGNRKSGLSLTWTDSFPGPQFETYQQTVASPDS---VDSNPYVSLDSP---PASPL 702

  Fly   387 PKAPPQESAEGQTQKLLFRLDKLERSWPWADREKII 422
            |.   .|.:....::.||...:..||   .|.:|.:
Zfish   703 PS---DELSPLPQRRKLFTFSRPPRS---RDTDKFL 732

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42319	NP_001137648.1	PDZ_signaling	45..119	CDD:238492	19/67 (28%)
grid2ipb	XP_009304908.1	PDZ_signaling	9..69	CDD:238492
		PDZ_signaling	80..156	CDD:238492
		HN_L-delphilin-R1_like	183..262	CDD:259820
		PDZ_signaling	335..410	CDD:238492	19/71 (27%)
		HN_L-delphilin-R2_like	451..530	CDD:259821	14/87 (16%)
		FH2	995..1360	CDD:280362
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900