DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42319 and pdlim3a

DIOPT Version :9

Sequence 1:	NP_001137648.1	Gene:	CG42319 / 36473	FlyBaseID:	FBgn0259219	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001019547.1	Gene:	pdlim3a / 554148	ZFINID:	ZDB-GENE-050505-1	Length:	307	Species:	Danio rerio

Alignment Length:	240	Identity:	55/240 - (22%)
Similarity:	88/240 - (36%)	Gaps:	44/240 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 WGFLITGGAEFHMPLTVFQVTPNGLADKAGIRLGDIILEINEEDASQLTLSQAHEKINSTPKKIH 115
            |||.:.||.:|..||||.:::|...|....:..|||||.|:...|..|..|:|...|.....::.
Zfish    13 WGFRLIGGRDFSQPLTVAKISPGSKASTVNLSPGDIILSIDGVSAENLMHSEAQTLIKDASYQLT 77

  Fly   116 FLLR---------NMEEDDPMG-QFEAGEEKSIVMRVPKPLPPPSGRIRASSIEMRLLEMQRKLS 170
            ..:.         ||.||:|.. ..||..::.      :|:.....| |||           ...
Zfish    78 LTVERPETKLWSPNMTEDNPFKMNLEAERQEH------RPIGAGHNR-RAS-----------PFV 124

  Fly   171 AIAEIPKILCSTLATVSQNFGRMSESEVDEDDVGEEEAYVQRKFSYDEDALDFELRNGEQAGDTD 235
            |.|.|.:.......|.:...|..|...:.:...|:.:..:..|........:.|          |
Zfish   125 AAANIDETRQVVSPTYNSPIGLYSSGNIQDALQGQLKGLIHNKAESPTKLSNIE----------D 179

  Fly   236 SDEEDLVLVREEDAEDVDVPKGAKQSKLLKDVTPESDYASEANYP 280
            ||...: |.:.::.::...|:.:...|.|     :|...||...|
Zfish   180 SDVYRM-LQKNQEEDEAHEPRQSGSFKAL-----QSFMNSEGTRP 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42319	NP_001137648.1	PDZ_signaling	45..119	CDD:238492	23/67 (34%)
pdlim3a	NP_001019547.1	PDZ_signaling	2..81	CDD:238492	23/67 (34%)
		DUF4749	134..214	CDD:292558	14/95 (15%)
		LIM_ALP_like	244..295	CDD:188746
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24214
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100