DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42319 and Pdlim1

DIOPT Version :9

Sequence 1:	NP_001137648.1	Gene:	CG42319 / 36473	FlyBaseID:	FBgn0259219	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_059061.1	Gene:	Pdlim1 / 54133	RGDID:	68324	Length:	327	Species:	Rattus norvegicus

Alignment Length:	263	Identity:	57/263 - (21%)
Similarity:	92/263 - (34%)	Gaps:	75/263 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 WGFLITGGAEFHMPLTVFQVTPNGLADKAGIRLGDIILEINEEDASQLTLSQAHEKINSTPKKIH 115
            |||.:.||.:|..||.:.:|||...|..|.:.:||:|..|:.||.|.:|..:|..||......:.
  Rat    14 WGFRLVGGKDFEQPLAISRVTPGSKAAIANLCIGDLITAIDGEDTSSMTHLEAQNKIKGCVDNMT 78

  Fly   116 FLLRNMEED--DPMGQFE----------AGEEKSIV------MRVPKPL---PPPSGRIRASSIE 159
            ..:...|:.  .|:...|          |.|.:.::      .|...|.   |.|..|:..:...
  Rat    79 LTVSRSEQKIWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAHNRSAMPFTASPAPGTRVITNQYN 143

  Fly   160 MRLLEMQRKLSAIAEIPKILCSTLATVSQNFGRMSESEVDEDDVGEEEAYVQRKFSYDEDALDFE 224
            .               |..|.|     |:|....:.:             |:.|.|
  Rat   144 S---------------PTGLYS-----SENISNFNNA-------------VESKTS--------- 166

  Fly   225 LRNGEQAGDTDS-----------DEEDLVLVREEDAEDVDVPKGAKQSKLLKDVTPESDYASEAN 278
             .:||:|....|           |:|..|....::.::::.|.....|.|:.....|||...:.|
  Rat   167 -ASGEEANSRPSAQPHPSGGLIIDKESEVYKMLQEKQELNEPPKQSTSFLVLQEILESDGKGDPN 230

  Fly   279 YPA 281
            .|:
  Rat   231 KPS 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42319	NP_001137648.1	PDZ_signaling	45..119	CDD:238492	24/67 (36%)
Pdlim1	NP_059061.1	PDZ_signaling	5..81	CDD:238492	24/66 (36%)
		DUF4749	136..228	CDD:292558	22/134 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	161..186		7/34 (21%)
		LIM_CLP36	258..309	CDD:188832
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	59	1.000	Domainoid score	I10378
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003437
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24214
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.100