DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42319 and Pdlim1

DIOPT Version :9

Sequence 1:	NP_001137648.1	Gene:	CG42319 / 36473	FlyBaseID:	FBgn0259219	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_058557.2	Gene:	Pdlim1 / 54132	MGIID:	1860611	Length:	327	Species:	Mus musculus

Alignment Length:	255	Identity:	63/255 - (24%)
Similarity:	97/255 - (38%)	Gaps:	59/255 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 WGFLITGGAEFHMPLTVFQVTPNGLADKAGIRLGDIILEINEEDASQLTLSQAHEKINSTPKKIH 115
            |||.:.||.:|..||.:.:|||...|..|.:.:||:|..|:.||.|.:|..:|..||......:.
Mouse    14 WGFRLVGGKDFEQPLAISRVTPGSKAAIANLCIGDLITAIDGEDTSSMTHLEAQNKIKGCADNMT 78

  Fly   116 FLLRNMEED--DPMGQFE----------AGEEKSIV------MRVPKPL---PPPSGRIRASSIE 159
            ..:...|:.  .|:...|          |.|.:.::      .|...|.   |.||.|:..:...
Mouse    79 LTVSRSEQKIWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAHNRSAMPFTASPAPSTRVITNQYN 143

  Fly   160 MRLLEMQRKLSAIAEIPKILCSTLATVSQNFGRMSESEVDEDDVGEE---EAYVQRKFSYDEDAL 221
            .               |..|.|: ..:| ||....||:....  |||   ...||...|
Mouse   144 S---------------PTGLYSS-ENIS-NFNNAVESKTSAS--GEEANSRPVVQPHPS------ 183

  Fly   222 DFELRNGEQAGDTDSDEEDLVLVREEDAEDVDVPKGAKQSKLLKDVTPESDYASEANYPA 281
                  |....|.||:...::   :|..|..:.||.:....:|:::. |||...:.|.|:
Mouse   184 ------GSLIIDKDSEVYKML---QEKQELNEPPKQSTSFLVLQEIL-ESDGKGDPNKPS 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42319	NP_001137648.1	PDZ_signaling	45..119	CDD:238492	24/67 (36%)
Pdlim1	NP_058557.2	PDZ_signaling	5..81	CDD:238492	24/66 (36%)
		DUF4749	136..228	CDD:292558	27/126 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	161..184		8/36 (22%)
		LIM_CLP36	258..309	CDD:188832
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003437
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24214
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.100