DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42319 and Ldb3

DIOPT Version :9

Sequence 1:	NP_001137648.1	Gene:	CG42319 / 36473	FlyBaseID:	FBgn0259219	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	XP_006252699.3	Gene:	Ldb3 / 498587	RGDID:	1564875	Length:	771	Species:	Rattus norvegicus

Alignment Length:	380	Identity:	72/380 - (18%)
Similarity:	123/380 - (32%)	Gaps:	107/380 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 WGFLITGGAEFHMPLTVFQVTPNGLADKAGIRLGDIILEINEEDASQLTLSQAHEKINSTPKKIH 115
            |||.:.||.:|:||||:.::||...|.::.:..||:::.|:..:...:|..:|..||.|....:.
  Rat    58 WGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLEAQNKIKSASYNLS 122

  Fly   116 FLLRNMEEDDPMGQFEAGEEKSIVMRVPKPLP------PPSGRIRASSIEMRLLEMQRKLSAIAE 174
            ..|:..:...|:        .:....:..|||      .||            |:....|:..:.
  Rat   123 LTLQKSKRPIPI--------STTAPPIQSPLPVIPHQKDPS------------LDTNSSLATPSP 167

  Fly   175 IPKILCSTLATVSQNFGRMSESEVDEDDVGEEEAYVQRKFSYDEDALDFELRNGEQAGDTDSDEE 239
            .|:...|...:.:..||....|...:..|.....                    |.:|.......
  Rat   168 SPEARASPGTSGTLEFGDTFSSSFSQTSVCTSHM--------------------EASGPVLPLGS 212

  Fly   240 DLVLVREEDAEDVDVPK---GAKQSKLLKDVTPESDYASE------------------------A 277
            .:.....|..:....||   |..|.:|..:  |...|::|                        .
  Rat   213 PVAKASSEGTQGSVSPKVLPGPSQPRLYNN--PIGLYSAETLREMAQMYQMSLRGKASGAGLLGG 275

  Fly   278 NYPANEASDDTESDDEDEPGSTVYFMKLPAAAAEDTYSSTEDEDDSDFLNTTYTWNLRNVPKLRI 342
            :.|..:.:.|:        .|.||      .|...|.|..|||.|.        | .|....|:.
  Rat   276 SLPVKDLAVDS--------ASPVY------QAVIKTQSKPEDEADE--------W-ARRSSNLQS 317

  Fly   343 NDAEAEGELTLGHQAREVPQQEQPQEKQPCLEPEP--------PKVRPATPTPKA 389
            .......::| |.:..:.|.:|..:.....:|..|        |.:..:.|:|.|
  Rat   318 RSFRILAQMT-GTEYMQDPDEEALRRSSTPIEHAPVCTSQATSPLLPASAPSPAA 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42319	NP_001137648.1	PDZ_signaling	45..119	CDD:238492	21/67 (31%)
Ldb3	XP_006252699.3	PDZ_signaling	50..126	CDD:238492	21/67 (31%)
		DUF4749	240..341	CDD:406377	22/126 (17%)
		PHA03247	<426..576	CDD:223021
		LIM1_ZASP_Cypher	595..646	CDD:188838
		LIM2_Enigma_like	654..705	CDD:188748
		LIM3_ZASP_Cypher	713..767	CDD:188844
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	59	1.000	Domainoid score	I10378
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24214
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.100