DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42319 and a

DIOPT Version :9

Sequence 1:	NP_001137648.1	Gene:	CG42319 / 36473	FlyBaseID:	FBgn0259219	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001014543.1	Gene:	a / 43852	FlyBaseID:	FBgn0000008	Length:	1329	Species:	Drosophila melanogaster

Alignment Length:	468	Identity:	77/468 - (16%)
Similarity:	139/468 - (29%)	Gaps:	154/468 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 SVPESKSKAPIIKVSCGIGDTDGYPAFDVDSDAYATKDDSRWGFLITGGAEFHMPLTVFQVTPNG 74
            |:|:...|:|::.:||..                          |.:.||.....:|   .|..|
  Fly    71 SLPDLHDKSPVMILSCTT--------------------------LASNGATATAAVT---ATATG 106

  Fly    75 LADKAGIRLGDIILEINEEDASQLTLSQAHEKI-NSTPKKIHFLLRNMEEDDPMGQFEAGEEKSI 138
            .|..:|..|       .::....|...|..:.: .:||.   .||...:....:......|..|:
  Fly   107 TAATSGGSL-------QQQQQQHLQHQQQQQPLRTATPT---CLLSGRQTPSAISVMSLQEATSL 161

  Fly   139 VMRVPKPLPPPS----------GRIRASSIEMRLLEMQRKLSAIAEIPKILCSTLATVSQNFGRM 193
            ..:..:|..||:          ..:...:....||......|:||.:
  Fly   162 HRQQQQPHQPPTIYVPVPTKLGNNVNTGNSSATLLLSYGSTSSIANL------------------ 208

  Fly   194 SESEVDEDDVGEEEAYVQRKFSYDEDALDFELRNGEQAGDTDSDEEDLVLVREEDAEDVDVPKGA 258
              .:..:....:.:.||.::......:..:| :....:|...|::..|.|          .|.|.
  Fly   209 --QQQQQQHAAQYQQYVAQRLHAASSSCLYE-KGSNASGGASSNKSSLSL----------TPNGH 260

  Fly   259 KQSKLLKDVTP----ESDYASEANYPANEASDDTESDDEDEPGSTVYFMKLPAAAAEDTYSSTED 319
            .....|....|    :.::.|. :.||.|||.::.|.......|.       :.:.:.:.|::..
  Fly   261 LPDYKLVTAMPVVVLDDEHKSN-SLPATEASRNSNSSSNMNGSSN-------SNSLDVSNSNSHS 317

  Fly   320 EDDSDFLNTT---YTWNLRNVPKLRI-------------------------------------ND 344
            ...:...:||   :||..|...||.:                                     :.
  Fly   318 GSSTSLASTTRNVFTWGKRMSRKLDLLKRSDSPAAAHKSHSDLRSLFHSPTHHKSGSGGSSGPSS 382

  Fly   345 AEAEGELTLGHQ------------AREVP-------QQEQPQEKQPCLEPEPPKVRPATPTPKAP 390
            |:|....|.|||            .:..|       .|:|.|::|...:....:.:.|..||  .
  Fly   383 AKASASPTGGHQNSSGSTTSTLKKCKSGPIETIKQRHQQQQQQQQSVQDVGTGQSQSAQSTP--T 445

  Fly   391 PQESAEGQTQKLL 403
            .|..|..:.||.|
  Fly   446 HQFQAAARPQKAL 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42319	NP_001137648.1	PDZ_signaling	45..119	CDD:238492	14/74 (19%)
a	NP_001014543.1	PDZ_signaling	775..865	CDD:238492
a	NP_001014543.1	PDZ_signaling	1230..1317	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900