DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42319 and dysc

DIOPT Version :9

Sequence 1:	NP_001137648.1	Gene:	CG42319 / 36473	FlyBaseID:	FBgn0259219	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001261810.1	Gene:	dysc / 39533	FlyBaseID:	FBgn0264006	Length:	1254	Species:	Drosophila melanogaster

Alignment Length:	284	Identity:	57/284 - (20%)
Similarity:	112/284 - (39%)	Gaps:	48/284 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 GFLITGGAEFHMPLTVFQVTPNGLADKAGIRLGDIILEINEEDASQLTLSQAHEKINSTPKKIHF 116
            |.:|.||.|:.:.:.|..|..:.:||::|:.:||.|||:|.:....:|..:|..:: ...|::..
  Fly   477 GLMIRGGVEYGLGIFVTGVDKDSVADRSGLMIGDEILEVNGQSFLDVTHDEAVGQL-KYHKRMSL 540

  Fly   117 LLRNME---------EDDPMGQF--------EAGEEKSIVMRVPKPLPPPSGRIRASSIEMRLLE 164
            ::|::.         |.:|...:        ..|:..::|....:.|.|   |...:|:...:.|
  Fly   541 VIRDVGKVPHSCTSIEMEPWDAYSPTGTRARRKGQIATMVEEKARSLLP---RHHFASLSYYIAE 602

  Fly   165 MQRKLSAIAEIPKILCSTLATVSQN--FGRMSESEVDEDDVGEEEAYVQRKFSYDEDALDFELRN 227
            ...|...|.....:|...|.|..::  ...:.|....||....:|...:|:  .|..::|...|.
  Fly   603 YSAKAMTIDAFVAVLLEMLDTYEKHTLVTEIRELVFPEDRTRYDELVYRRE--RDPYSVDRHRRK 665

  Fly   228 GEQAGDTDSDEEDLVLV----REEDAED------VDV-----------PKGAKQSKLLKDVTPES 271
            |:.|.|.....:||.::    |...::.      .|:           |..|  ..:|....|.|
  Fly   666 GDPARDLPVTADDLEIIAATGRSPSSDSGLGMTVTDIYKRPALQLPHRPMSA--GPILHRSQPAS 728

  Fly   272 DYASEANYPANEASDDTESDDEDE 295
            .|.:.:|..::..|...:...:.:
  Fly   729 HYQTGSNQSSSSLSPPQQQQQQQQ 752

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42319	NP_001137648.1	PDZ_signaling	45..119	CDD:238492	19/66 (29%)
dysc	NP_001261810.1	PDZ_signaling	294..380	CDD:238492
		PDZ_signaling	466..543	CDD:238492	19/66 (29%)
		HN_L-whirlin_R2_like	573..653	CDD:259823	16/82 (20%)
		PDZ_signaling	886..971	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900