DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42319 and Zasp67

DIOPT Version :9

Sequence 1:	NP_001137648.1	Gene:	CG42319 / 36473	FlyBaseID:	FBgn0259219	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_648358.2	Gene:	Zasp67 / 39148	FlyBaseID:	FBgn0036044	Length:	730	Species:	Drosophila melanogaster

Alignment Length:	400	Identity:	106/400 - (26%)
Similarity:	163/400 - (40%)	Gaps:	63/400 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 DDSRWGFLITGGAEFHMPLTVFQVTPNGLADKAGIRLGDIILEINEEDASQLTLSQAHEKINSTP 111
            |:..|||.:.|||::..||||.:||...:||:||:|:.|||:.||:..|:.||..:||..|..:.
  Fly    11 DNVPWGFRLVGGADYDYPLTVVKVTEGSIADEAGLRVEDIIVRINDTAATPLTHDEAHRLIMGSG 75

  Fly   112 KKIHF-LLRNMEED--DPMGQFEAGEEKSIVMRVP--KPLPPPSGRIRASSIEMRLLE------M 165
            ...:| :.|..|||  :.:.:|...|.......:|  .|.|.||......:...|..|      :
  Fly    76 SVFYFGVYRENEEDAYECLKKFPTSEGSLTKSPMPTISPSPTPSLSQLTETTNARTPEPEPFVPL 140

  Fly   166 QRKLSA---IAEIPKILCSTLATVSQNFGRMSE--SEVDEDDVGEEEAYVQRKFSYDEDALDFEL 225
            .|:|:|   .|...::....||...|   .|||  ||....||...:|..|.    ||..|..|.
  Fly   141 PRELAAATMAAPAVEVDVDVLAECRQ---PMSEVHSEEKRGDVNGHDAPGQA----DEGGLPVEN 198

  Fly   226 RNGEQAGDTD----SDEEDLVLVREEDAEDVDVPKGAKQSKLLKD----------------VTPE 270
            .......|..    |:.:::.||.||.|.   |..|  :|::||:                |...
  Fly   199 LYLPDLPDRPCSALSERQEIKLVEEEIAA---VLSG--ESEVLKEHNVLGVNFYRIFPKPGVCMS 258

  Fly   271 SDYASEANYPANEASDDTESDDEDEPGSTVYFMKLPAAAAEDTYSSTEDEDDSDFLNTTYTWNLR 335
            ||.....|....:..  .|.|.|:...||  |::.|......:..|.|.|..:  .|......::
  Fly   259 SDVLRSLNEEVTKTK--LEKDKENRQWST--FLQRPNRPVPKSKQSLEAERRA--ANAYKVTIVK 317

  Fly   336 NVPKLRINDAEAEGELTLGHQAREVPQQEQPQEKQPCLEPEPPKVRPATPTP---------KAPP 391
            :.|:.:....||:.........:||.::|:....:..:||||...:...|.|         :.|.
  Fly   318 SAPREKSPMPEAKPAPKEATPPKEVEKKEEEPVPEEVVEPEPEPEKDEEPLPTDSEVPNLEQLPE 382

  Fly   392 QESAEGQTQK 401
            .|..:.|.:|
  Fly   383 TELPDEQPEK 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42319	NP_001137648.1	PDZ_signaling	45..119	CDD:238492	30/72 (42%)
Zasp67	NP_648358.2	PDZ_signaling	2..75	CDD:238492	29/63 (46%)
Zasp67	NP_648358.2	DUF4749	653..>699	CDD:292558
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm41321
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24214
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5637
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.940