DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42319 and baz

DIOPT Version :9

Sequence 1:	NP_001137648.1	Gene:	CG42319 / 36473	FlyBaseID:	FBgn0259219	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001036283.1	Gene:	baz / 32703	FlyBaseID:	FBgn0000163	Length:	1520	Species:	Drosophila melanogaster

Alignment Length:	443	Identity:	93/443 - (20%)
Similarity:	150/443 - (33%)	Gaps:	109/443 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 SVP-ESKSKAPIIKVSCGIGDTDGYPAFDVDSDAYATKDDSRWGFLITGGAEFHMPLTVFQVTPN 73
            |:| |||.|.|:.:....|.:.||.....::.  |.    |..|.......|....|.|..|.|.
  Fly   308 SLPRESKRKEPLGQAYESIREKDGEMLLIINE--YG----SPLGLTALPDKEHGGGLLVQHVEPG 366

  Fly    74 GLADKAGIRLGDIILEINEEDASQLTLSQAHEK----INSTPKKIHFLL----RNMEEDDPMGQF 130
            ..|::..:|..|.|||||......||.||..|:    :.|:..::..|.    |..:.|..:.:.
  Fly   367 SRAERGRLRRDDRILEINGIKLIGLTESQVQEQLRRALESSELRVRVLRGDRNRRQQRDSKVAEM 431

  Fly   131 EAGEEKSIVMRVPKPLPPPSGRIRASSIEMRLLEMQRKLSAIAEI-----PKILCSTLATVSQNF 190
               .|.:.|....||...|.|    :|::   :...|||....||     |..|..::.|.....
  Fly   432 ---VEVATVSPTRKPHAAPVG----TSLQ---VANTRKLGRKIEIMLKKGPNGLGFSVTTRDNPA 486

  Fly   191 GRMSESEVDEDDVGEEEAYVQRKFSYDEDALDFELRNGEQAGDTD------SDEEDLVLVREEDA 249
            |            |....|::..........|..|:.|::..:.|      ..:.|:|.:..
  Fly   487 G------------GHCPIYIKNILPRGAAIEDGRLKPGDRLLEVDGTPMTGKTQTDVVAILR--- 536

  Fly   250 EDVDVPKGAKQSKLLKDVTPESDYASEANYPANEASDDTESDDEDEPGSTVYFMKLPAAAAEDTY 314
               .:|.||....:   |:.:.:.|.:|:.||.:::....:.....|.       :|||||.
  Fly   537 ---GMPAGATVRIV---VSRQQELAEQADQPAEKSAGVAVAPSVAPPA-------VPAAAAP--- 585

  Fly   315 SSTEDEDDSDFLNTTYTWNLRNVPKLRINDAEAEGELTLGHQAREVPQQEQPQEKQPCLEPEPPK 379
                                  .|.:.:..:.:...| ..||     ||.|..|.|..::...
  Fly   586 ----------------------APPIPVQKSSSARSL-FTHQ-----QQSQLNESQHFIDAGS-- 620

  Fly   380 VRPATPTPKAPPQESAEGQTQKLLFRLDKLERSWPWADREK----IIYKQSTC 428
             ..|......||..::....::|...:       |..|.||    :..|..||
  Fly   621 -ESAASNDSLPPSSNSWHSREELTLHI-------PVHDTEKAGLGVSVKGKTC 665

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42319	NP_001137648.1	PDZ_signaling	45..119	CDD:238492	22/81 (27%)
baz	NP_001036283.1	DUF3534	<62..174	CDD:288873
		PDZ_signaling	341..412	CDD:238492	21/74 (28%)
		CRS1_YhbY	<390..>436	CDD:294440	10/48 (21%)
		PDZ_signaling	462..548	CDD:238492	17/106 (16%)
		PDZ_signaling	<686..753	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900