DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42319 and Pdzd7

DIOPT Version :9

Sequence 1:	NP_001137648.1	Gene:	CG42319 / 36473	FlyBaseID:	FBgn0259219	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001099832.2	Gene:	Pdzd7 / 293996	RGDID:	1309882	Length:	1031	Species:	Rattus norvegicus

Alignment Length:	418	Identity:	83/418 - (19%)
Similarity:	143/418 - (34%)	Gaps:	127/418 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 VDSDAYATKDDS--------------RWGFLITGGAEFHMPLTVFQVTPNGLADKAGIRLGDIIL 88
            ::|...|..|:|              |.||.:.||:|..:.:.|.:|.....|::||:.:||.|.
  Rat    70 INSPIEANSDESDIIHAVCVEKSPSGRLGFSVRGGSEHGLGIFVSKVEEGSSAERAGLCVGDKIT 134

  Fly    89 EINEEDASQLTLSQAHEKINSTPKKIHFLLRNMEEDDPMGQFEAGEEKSIVMRVPKPLPPPSGRI 153
            |:|.......|:..|...:.|: .::|.::|.|.                  |||        .|
  Rat   135 EVNGLSLESTTMGSAVRLLTSS-SRLHMMVRRMG------------------RVP--------GI 172

  Fly   154 RASSIEMRLLEMQRKLSAIAEIPKILCSTLATVSQNFGRMSESEVDEDDVGEEEAYVQRKFSYDE 218
            :.|..:...:::..:...:.:     ||:..:.|.:          ||.|   ...|....:.|:
  Rat   173 KFSKEKTTWVDVVNRRLVVEK-----CSSTPSDSSS----------EDGV---RRIVHLYTTSDD 219

  Fly   219 DALDFELRNGEQAG---------------DTDSDEEDLVL----VREED---AEDVDVPKGAKQS 261
            ..|.|.:|.|::.|               :......|.||    ||.:|   ::.|:|.||....
  Rat   220 FCLGFNIRGGKEFGLGIYVSKVDHGGLAEENGIKVGDQVLAANGVRFDDISHSQAVEVLKGQTHI 284

  Fly   262 KL----------------------------LKDVTPESDYASEANYPANEA---SDDTESDDED- 294
            .|                            |:.::|.|:.:|..:..|:.|   |....||..|
  Rat   285 MLTIKETGRYPAYKEMVSEYCWLDRLSNGVLQQLSPASESSSSVSSYASSAPCSSGSLPSDRMDV 349

  Fly   295 -----EPGSTVYFMKLPAAAAEDTYSSTEDEDDSDFLNTTYTW-NLRNVPKLRINDAEAEGELTL 353
                 :|.|     :.|.....||...||.:...   :...|| ::|....||.....::|..:.
  Rat   350 CLGPEDPTS-----QGPGWGRADTAMQTEPDMGG---SRVETWCSVRPTVILRDTAIRSDGPSST 406

  Fly   354 GHQAREVPQQEQPQEKQPCLEPEPPKVR 381
            .|....:.:..:.........|.||..|
  Rat   407 RHLDSALSESPKTALLLALSRPRPPITR 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42319	NP_001137648.1	PDZ_signaling	45..119	CDD:238492	22/87 (25%)
Pdzd7	NP_001099832.2	PDZ_signaling	84..164	CDD:238492	20/80 (25%)
		PDZ_signaling	209..289	CDD:238492	18/79 (23%)
		HN_PDZD7_like	555..632	CDD:259824
		PDZ_signaling	866..954	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900