DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42319 and Pdlim7

DIOPT Version :9

Sequence 1:	NP_001137648.1	Gene:	CG42319 / 36473	FlyBaseID:	FBgn0259219	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	XP_038951356.1	Gene:	Pdlim7 / 286908	RGDID:	628769	Length:	464	Species:	Rattus norvegicus

Alignment Length:	420	Identity:	84/420 - (20%)
Similarity:	144/420 - (34%)	Gaps:	158/420 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 VDSDAYATKDDSRWGFLITGGAEFHMPLTVFQVTPNGLADKAGIRLGDIILEINEEDASQLTLSQ 102
            :||.....:..:.|||.:.||.:|::||::.::||.|.|.:||:.:||.:|.|:.|:|..||..:
  Rat     1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIE 65

  Fly   103 AHEKINSTPKKIHFLLRNMEEDDPMGQFEAGEEKSIVMRVPKPLPPPSGRIRASSIEMRLLEMQR 167
            |..||.:                      .||..|:            |..||...:.:   .|:
  Rat    66 AQNKIRA----------------------CGERLSL------------GLSRAQPAQSK---PQK 93

  Fly   168 KLSAIAEIPKILCSTLATVSQN---FGRMSESEVDEDDVGEEEAYVQRKFSYDEDALDFELRNGE 229
            .|:..|:.|:...:..|::::.   ||....:                     :.||.   :||.
  Rat    94 ALTPPADPPRYTFAPSASLNKTARPFGAPPPT---------------------DSALS---QNGC 134

  Fly   230 QAGDTDSDEEDLVLVREEDAEDVDVPKGAKQSKLLKDVTPESDYASEANYPANEASDDTESDDED 294
            :                        |..::|  ||:.:.|::.        .....::|| |...
  Rat   135 R------------------------PLTSQQ--LLRQLVPDAS--------KQRLMENTE-DWRP 164

  Fly   295 EPGS--TVYFMKLPAAAAEDTYSSTEDEDDSDFLNTTYTWNLRNVPKLRINDAEAEGELTLGHQA 357
            .||:  :..|..|    |..|.:....:.|.:|:..:     ..||:   .:|.|
  Rat   165 RPGTGQSRSFRIL----AHLTGTEFMQDPDEEFMKKS-----SQVPR---TEAPA---------- 207

  Fly   358 REVPQQEQPQEKQPCLEPEPPKVRPATPTPKAPP---------QESAEGQTQKLLFRLDKLERSW 413
               |....|||..|         .|.||:|.:.|         :..|..:|..:|.|..:.....
  Rat   208 ---PASTIPQESWP---------GPTTPSPTSRPPWAVDPAFAERYAPDKTSTVLTRHSQPATPT 260

  Fly   414 PWADREKIIY--------------KQSTCH 429
            |..:|..|:.              |...||
  Rat   261 PLQNRTSIVQAAAGGGTGGGSNNGKTPVCH 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42319	NP_001137648.1	PDZ_signaling	45..119	CDD:238492	25/73 (34%)
Pdlim7	XP_038951356.1	PDZ_signaling	5..79	CDD:238492	27/95 (28%)
		PHA03247	<11..261	CDD:223021	76/379 (20%)
		DUF4749	<163..192	CDD:406377	7/32 (22%)
		LIM1_Enigma	289..340	CDD:188836	2/2 (100%)
		LIM2_Enigma	348..399	CDD:188840
		LIM3_Enigma	407..461	CDD:188842
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	59	1.000	Domainoid score	I10378
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24214
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.100