DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42319 and Pdlim4

DIOPT Version :9

Sequence 1:	NP_001137648.1	Gene:	CG42319 / 36473	FlyBaseID:	FBgn0259219	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001380800.1	Gene:	Pdlim4 / 24915	RGDID:	3575	Length:	335	Species:	Rattus norvegicus

Alignment Length:	185	Identity:	45/185 - (24%)
Similarity:	65/185 - (35%)	Gaps:	68/185 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 SRWGFLITGGAEFHMPLTVFQVTPNGLADKAGIRLGDIILEINEEDASQLTLSQAHEKIN----- 108
            |.|||.:.||.:|..|||:.:|.....|..|.:..||:|..||.|....:|..:|..:|.
  Rat    11 SPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTHLEAQNRIKGCHDH 75

  Fly   109 --------------STP------KKIHFLLRNMEEDDPMGQFE-------AGEEKSIVMRV---- 142
                          |:|      .:||.        ||..|..       |...:|.:..:
  Rat    76 LTLSVSRPENKNWPSSPDDKAQAHRIHI--------DPEAQASLLQDGSPATSRRSSISGISLED 132

  Fly   143 -----------PKPLPPPSGRIRASSIEMRLLEMQRKLSAI-------AEIPKIL 179
                       |..||.|.   ..||.|:.|   ..::||:       |:.|:||
  Rat   133 NRSGLGSPYGQPPRLPVPH---NGSSNEVTL---PSQMSALHVSPPPSADTPRIL 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42319	NP_001137648.1	PDZ_signaling	45..119	CDD:238492	26/94 (28%)
Pdlim4	NP_001380800.1	PDZ_signaling	2..80	CDD:238492	22/68 (32%)
		DUF4749	139..235	CDD:406377	14/49 (29%)
		LIM_RIL	260..312	CDD:188835
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	59	1.000	Domainoid score	I10378
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24214
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.100