DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42319 and Lnx1

DIOPT Version :9

Sequence 1:	NP_001137648.1	Gene:	CG42319 / 36473	FlyBaseID:	FBgn0259219	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001153049.1	Gene:	Lnx1 / 16924	MGIID:	1278335	Length:	728	Species:	Mus musculus

Alignment Length:	147	Identity:	40/147 - (27%)
Similarity:	68/147 - (46%)	Gaps:	35/147 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 KDDSR-WGFLITGGA---EFHMPLTVFQVTPNGLADKAG-IRLGDIILEINEEDASQLTLSQAHE 105
            ||.|. .|..:.|||   |:.:|:.|..|.|.|:..:.| |:.|||:|.:|..:.::::.::|..
Mouse   513 KDPSESLGMTVGGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVNGIELTEVSRTEAVA 577

  Fly   106 KINSTPKKIHFLLRNMEEDDPMGQFEAGEEKSIVMRVPKPL------PPPSGRIRASSIEMRLLE 164
            .:.|.|..:  :|:.:|    :.:.||.|:.|     |..|      .||..  .:.|..|.|
Mouse   578 ILKSAPSSV--VLKALE----VKEQEAQEDCS-----PAALDSNHNVTPPGD--WSPSWVMWL-- 627

  Fly   165 MQRKLSAIAEIPKILCS 181
                     |:|:.||:
Mouse   628 ---------ELPQYLCN 635

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42319	NP_001137648.1	PDZ_signaling	45..119	CDD:238492	23/77 (30%)
Lnx1	NP_001153049.1	mRING-HC-C3HC3D_LNX1	42..83	CDD:319693
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	185..220
		NPXY motif	185..188
		Interaction with MAGEB18. /evidence=ECO:0000250	186..244
		PDZ_signaling	276..360	CDD:238492
		PDZ_signaling	384..464	CDD:238492
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	481..500
		PDZ_signaling	506..589	CDD:238492	23/77 (30%)
		PDZ_signaling	637..721	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900