DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42319 and FRMPD2

DIOPT Version :9

Sequence 1:NP_001137648.1 Gene:CG42319 / 36473 FlyBaseID:FBgn0259219 Length:452 Species:Drosophila melanogaster
Sequence 2:NP_001018081.4 Gene:FRMPD2 / 143162 HGNCID:28572 Length:1309 Species:Homo sapiens


Alignment Length:340 Identity:71/340 - (20%)
Similarity:121/340 - (35%) Gaps:80/340 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    46 KDDSRWGFLITGGAEFHMP---LTVFQVTPNGLADKAG-IRLGDIILEINEEDASQLTLSQAHEK 106
            |:|...||.:|||....:|   :.|..:.|.|.|.|.| |..||.:|:::......||..||.:.
Human   955 KEDGTLGFSVTGGINTSVPYGGIYVKSIVPGGPAAKEGQILQGDRLLQVDGVILCGLTHKQAVQC 1019

  Fly   107 INSTPKKIHFLLR----NMEEDDPMGQFEAGEEKSIVMRVPKPLPPPSGRIRAS---SIEMRLLE 164
            :....:....:|.    ...:..|......|:|::.|..|......||..:..:   ..|::|.:
Human  1020 LTGPGQVARLVLERRVPRSTQQCPSANDSMGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKK 1084

  Fly   165 MQRKLS-AIAEIPKILCSTLATVSQNFGRMSESEVDEDD--------------------VGEEEA 208
            ....|. :..::.|..||.|.:......|:...:..|::                    :.:|..
Human  1085 NANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVL 1149

  Fly   209 YVQRKFSYDE------------DALDFELRNGEQAGD--------TDS------DEEDLVLVREE 247
            ::.|....:.            ..|:.|.:..|.:.|        |||      |:||    ...
Human  1150 HLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQED----SWR 1210

  Fly   248 DAEDVDVPKGAKQSKLLKDVTPESDYAS--EANYPANE----ASDDTESDDEDEPGSTVYFMKLP 306
            |:...|..:|.       .:.|||...:  ||.:..|.    ||..|.|     |.|..:..||.
Human  1211 DSASPDAGEGL-------GLRPESSQKAIREAQWGQNRERPWASSLTHS-----PESHPHLCKLH 1263

  Fly   307 AAAAEDTYSSTEDED 321
            ....|.|.:::.::|
Human  1264 QERDESTLATSLEKD 1278

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42319NP_001137648.1 PDZ_signaling 45..119 CDD:238492 22/76 (29%)
FRMPD2NP_001018081.4 KIND 15..197 CDD:214801
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 214..249
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 266..302
B41 346..550 CDD:214604
FERM_C_PTPH13 546..647 CDD:270008
PDZ_signaling 773..857 CDD:238492
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 859..880
PDZ 947..1034 CDD:214570 23/78 (29%)
PDZ 1078..1167 CDD:214570 11/88 (13%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1204..1228 8/34 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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