DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42319 and SYNJ2BP-COX16

DIOPT Version :9

Sequence 1:	NP_001137648.1	Gene:	CG42319 / 36473	FlyBaseID:	FBgn0259219	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001189476.1	Gene:	SYNJ2BP-COX16 / 100529257	HGNCID:	48350	Length:	191	Species:	Homo sapiens

Alignment Length:	164	Identity:	32/164 - (19%)
Similarity:	64/164 - (39%)	Gaps:	26/164 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 TKDDSRWGFLITGGAEFH-----MPLTVFQVTPNGLADKAG-IRLGDIILEINEEDASQLTLSQA 103
            |:..|..||.|.||.:..     ..:.|.::..||.|...| ::.||.||.:|.:|...|....|
Human    17 TRGPSGLGFNIVGGTDQQYVSNDSGIYVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDA 81

  Fly   104 HEKINSTPKKIHFLL--RNMEEDDPMGQFEAGEEKSIVMRVPKPLPPPSGRIRASSIEMRLLEMQ 166
            .:...:....:...:  |...::.|:|....|:        |..:|.....:...::.|...|::
Human    82 VDLFRNAGYAVSLRVQHRLQVQNGPIGHRGEGD--------PSGIPIFMVLVPVFALTMMDPELE 138

  Fly   167 RKLSAIAEIPKILCSTLATVSQNFGRMSESEVDE 200
            :||.          ....::...:.::.:|:.|:
Human   139 KKLK----------ENKISLESEYEKIKDSKFDD 162

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42319	NP_001137648.1	PDZ_signaling	45..119	CDD:238492	20/81 (25%)
SYNJ2BP-COX16	NP_001189476.1	PDZ_signaling	13..97	CDD:238492	20/79 (25%)
		DegQ	<16..77	CDD:223343	18/59 (31%)
		COX16	<133..173	CDD:290843	5/40 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900