DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42319 and grip2

DIOPT Version :9

Sequence 1:	NP_001137648.1	Gene:	CG42319 / 36473	FlyBaseID:	FBgn0259219	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	XP_031757025.1	Gene:	grip2 / 100495373	XenbaseID:	XB-GENE-854056	Length:	1115	Species:	Xenopus tropicalis

Alignment Length:	275	Identity:	64/275 - (23%)
Similarity:	100/275 - (36%)	Gaps:	68/275 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 DTDGYPAFDVDSDAYATKDDSRWGFLITGGAEFHMPLTVFQVTPNGLADKAG-IRLGDIILEINE 92
            :|.|...:.|:...|.    ...|..|:|..|...|:.:..:|..|||::.| |.:||.||.||.
Frog   691 ETSGAIIYTVELKRYG----GPLGITISGTEEPFDPIVISGLTKRGLAERTGAIHIGDRILAINN 751

  Fly    93 EDASQLTLSQAHEKINSTPKKIHFLLRNMEEDDPMGQFEAGEEKSIVMRVPK------PLPPPSG 151
            .......||:|          ||.|..            |||  ::.:::.|      |......
Frog   752 VSLKGKPLSEA----------IHLLQM------------AGE--TVTLKIKKQAERIFPQRLSDS 792

  Fly   152 RIRASSIEMRLLEMQR--KLSAI--AEIPKILCSTLAT----------------VSQNFG----- 191
            ....|..|..|.:.|:  |||.|  ..:|.: .|.|.:                |.|..|
Frog   793 MNEGSDPEDDLTDSQKTSKLSDIYSTAVPSV-DSALESWDGSGIDAGYGSQGTYVPQAVGISLHP 856

  Fly   192 ---RMSESEVDEDDVGEEEAYVQRKFSYDEDALDFELRNGEQAGDTDSDEED-LVLVREEDAEDV 252
               |.|..:.....|...::|.....|::|...:...|...|....::|.:| ...|..|..||:
Frog   857 HEWRTSRQKSSTPPVEHRKSYPFLDGSFNEQDWEKPTRYPSQPNGLEADHDDSFWRVFGEALEDL 921

  Fly   253 DVPKGAKQSKLLKDV 267
            :.   ..||:||:::
Frog   922 ET---CGQSELLREI 933

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42319	NP_001137648.1	PDZ_signaling	45..119	CDD:238492	23/74 (31%)
grip2	XP_031757025.1	PDZ_signaling	87..169	CDD:238492
		PDZ_signaling	187..272	CDD:238492
		PDZ_signaling	287..370	CDD:238492
		PDZ_signaling	499..585	CDD:238492
		PDZ_signaling	598..681	CDD:238492
		PDZ_signaling	697..778	CDD:238492	28/108 (26%)
		PDZ_signaling	1007..1084	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910