DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4712 and Ccdc96

DIOPT Version :9

Sequence 1:	NP_610856.1	Gene:	CG4712 / 36469	FlyBaseID:	FBgn0033818	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_080001.1	Gene:	Ccdc96 / 66717	MGIID:	1913967	Length:	584	Species:	Mus musculus

Alignment Length:	681	Identity:	127/681 - (18%)
Similarity:	236/681 - (34%)	Gaps:	190/681 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ETENNEEPQIDLLEENEA-VRSLADEVLSRFSGDSKKSVSVNISMVSMSSNENSEERL-KIIRKE 64
            |.|...||:.....|.|: .:.::|      |..:|.|..::.:.|.:..:..:.|.. :.:.:|
Mouse    41 EPEPKPEPEPTQGREPESETQPVSD------SSKAKDSEGIDYAHVEVPESPGAAETAGEAVSRE 99

  Fly    65 ERKLAIKDIMNRLKERDAEEMKMKKSGEQEGDQREDEMASKSQDSIQRHMSISQVEEQDDETLLW 129
            ...|            ...:.|.|...::..|:.|||               .:.|::|::
Mouse   100 PESL------------PQTQPKTKPESKEPEDKDEDE---------------DEDEDEDED---- 133

  Fly   130 TKLGEDIDSDNRRTTDIAPAADTLDAVNAEDEDMLDLIETPSESDSEAPVTERSKS-IDPMKVAV 193
                ||.|.|                   ||||..:..:.|.:...:....:|.:| ..|
Mouse   134 ----EDEDED-------------------EDEDEGEERDRPEKPKGKGKREKRKESRFRP----- 170

  Fly   194 KSLMLVPSLSDISLPSAPPTSRKSSHSIKSNRSLIFKSSPTDGNSSFDTEESEEESTIGPIDPRT 258
             ||.|...:.:.:.|.......|:..|:|..          |......|:....:||...:.|
Mouse   171 -SLPLTTIVEEGAAPGPQAAKEKARESLKKR----------DSEEIEGTDRERHKSTEEQLHP-- 222

  Fly   259 PMDQLYDSLSICESLAPIKDEFSRTTALEKERNDYMGFEQLFTVTTEHLETDEIDVAAQLRTIET 323
                           ...|:|       ||::.               ..|:|.:..|.::.::.
Mouse   223 ---------------GEAKEE-------EKQKG---------------ASTEEFEWTADMQKLQE 250

  Fly   324 SQVISEFINHLIHKVVMPEHRGTEEYIRVRLDKEKLLVALQNEVHDYTSVRDHNKQLEERMVDYF 388
            .|:..|.:.. .|.:::..:|    |.|..:       .||.::|:  ::|....:......|
Mouse   251 QQLRGELVEQ-YHSLLVERNR----YQRYNM-------YLQQKIHE--TLRKKGLEAAAEPGD-- 299

  Fly   389 RRTKNFRYFDRLTPNAESTYSRRLDHALTYLS---------------YGQERLIRVREKYGILMT 438
                  :..:..:|..|..|       |.||:               |.||    |||
Mouse   300 ------KSAEPESPEKEQAY-------LRYLAMLEELKKQEADDLEWYRQE----VRE------- 340

  Fly   439 TAFLDLANAMNIVLSTEHHLEQTLKR---ILVRPDAETDFLKRLVARE---LRLMADHR-NQISD 496
              ...........:..|....|.||:   :.|.....|...::...||   |:.:.|.: .::|.
Mouse   341 --LKQQCQEKQTRVEKEWRRFQALKKQVVMQVMGSCRTRGGRQAALREVEQLQALEDKKEKEMSA 403

  Fly   497 ARLLLMSQKHTLARILEKIRDVETVCDGVSLNDF--ISVQNKTIGLEKKIEERNIELKRQRRLYH 559
            .||..:..|.:|.....:::..|.:.:|:.|.||  :.::|:|  ..:|:||||.||.:.|....
Mouse   404 VRLENVQLKQSLVHFETRMKAQEDLAEGLLLIDFEQLKIENQT--FNEKVEERNEELLKLRTKVT 466

  Fly   560 TELHMTKHNREKSHELKNKIHVLKDNLLEKHKLKNKLKSELCRRKLEHKAIRRRMRDLTCQGGIL 624
            :.:.:..|.:||...:..:....|..|.|........:..|.:.|....::|.....|:.:.|:|
Mouse   467 SNVQIITHVKEKLSFIDTENSCKKAQLSEVDAQVALGRDLLTKTKQARDSLRIDNVKLSQKCGLL 531

  Fly   625 AMPALMYDYDRTVAYVREKEKMVSSLRETLK 655
            ...:|:.|.:..|    ||.:|::...|:||
Mouse   532 GKESLLRDLEEKV----EKTEMLNRRLESLK 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4712	NP_610856.1	DUF4201	487..662	CDD:290581	42/172 (24%)
Ccdc96	NP_080001.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..243		52/316 (16%)
Ccdc96	NP_080001.1	DUF4201	394..570	CDD:290581	42/171 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	59	1.000	Domainoid score	I10603
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	92	1.000	Inparanoid score	I5074
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15654
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.150