DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mp20 and Cnn3

DIOPT Version :9

Sequence 1:	NP_001014522.2	Gene:	Mp20 / 36468	FlyBaseID:	FBgn0002789	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	NP_082320.1	Gene:	Cnn3 / 71994	MGIID:	1919244	Length:	330	Species:	Mus musculus

Alignment Length:	182	Identity:	72/182 - (39%)
Similarity:	107/182 - (58%)	Gaps:	8/182 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LERAVRAKIASKRNPEMDKEAQEWIEAIIAEKFPAGQSYEDVLKDGQVLCKLINVLSPNAVPKVN 67
            |...|:.|||||.:.:.:::.:.|||.:..  ...|.:::..||||.:||:|||.|.|.:|.|||
Mouse    12 LSAEVKNKIASKYDQQAEEDLRNWIEEVTG--LGIGTNFQLGLKDGIILCELINKLQPGSVKKVN 74

  Fly    68 SSGGQFKFMENINNFQKALKEYGVPDIDVFQTVDLYEKKDIANVTNTIFAL-GRATYK--HADFK 129
            .|...:..:|||.||.||::.||:...|:|:..||:|..::..|..|:.|| |.|..|  |....
Mouse    75 ESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTTLVALAGLAKTKGFHTTID 139

  Fly   130 GPFLGPKPADECKRDFTEEQLKAGQTIVGLQAGSNKGATQAGQNLGAGRKIL 181
               :|.|.|::..|.|.|.:|||||:::|||.|:||.|:|||......|:.|
Mouse   140 ---IGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTNKCASQAGMTAYGTRRHL 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mp20	NP_001014522.2	SCP1	7..179	CDD:227526	69/174 (40%)
		CH	18..121	CDD:237981	39/103 (38%)
		Calponin	158..178	CDD:278814	10/19 (53%)
Cnn3	NP_082320.1	CH	28..125	CDD:237981	36/98 (37%)
		Calponin-like 1	164..189		12/25 (48%)
		Calponin	164..187	CDD:306832	11/22 (50%)
		Calponin-like 2	204..229
		Calponin	204..226	CDD:306832
		Calponin-like 3	243..268
		Calponin	243..266	CDD:306832
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	279..330
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	89	1.000	Domainoid score	I7812
eggNOG	1	0.900	-	-		E1_COG5199
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D488325at33208
OrthoFinder	1	1.000	-	-		FOG0000270
OrthoInspector	1	1.000	-	-		mtm8680
orthoMCL	1	0.900	-	-		OOG6_102866
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2278
SonicParanoid	1	1.000	-	-		X194
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.750