DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mp20 and cnn1b

DIOPT Version :9

Sequence 1:	NP_001014522.2	Gene:	Mp20 / 36468	FlyBaseID:	FBgn0002789	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	XP_701038.5	Gene:	cnn1b / 572250	ZFINID:	ZDB-GENE-091118-54	Length:	296	Species:	Danio rerio

Alignment Length:	182	Identity:	68/182 - (37%)
Similarity:	111/182 - (60%)	Gaps:	8/182 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LERAVRAKIASKRNPEMDKEAQEWIEAIIAEKFPAGQSYEDVLKDGQVLCKLINVLSPNAVPKVN 67
            |...|::|:|.|.:|:.::|.:.||..:...|.|  :::.:.||||.:||:|||.|.|.:|.|:|
Zfish    13 LSAEVKSKLAHKYDPQKEEELRMWISDVTGRKLP--ENFMEGLKDGVLLCELINTLQPGSVRKIN 75

  Fly    68 SSGGQFKFMENINNFQKALKEYGVPDIDVFQTVDLYEKKDIANVTNTIFAL-GRATYK--HADFK 129
            :|...:..:|||.||.:|::|||:...::|:..||:|..:...|.:|:.|| |.|..|  |:.:.
Zfish    76 NSPQNWHQLENIGNFVRAIQEYGLKPHEIFEANDLFENVNHTQVQSTLIALAGMAKSKGFHSKYD 140

  Fly   130 GPFLGPKPADECKRDFTEEQLKAGQTIVGLQAGSNKGATQAGQNLGAGRKIL 181
               :|.|.|::.:|.|..|:||.|:.|:|||.|:||.|:|.|......|:.|
Zfish   141 ---IGVKYAEKQQRRFAPEKLKEGRNIIGLQMGTNKFASQKGMTSYGTRRHL 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mp20	NP_001014522.2	SCP1	7..179	CDD:227526	65/174 (37%)
		CH	18..121	CDD:237981	38/103 (37%)
		Calponin	158..178	CDD:278814	9/19 (47%)
cnn1b	XP_701038.5	SCP1	17..179	CDD:227526	64/166 (39%)
		CH	30..126	CDD:278723	35/97 (36%)
		Calponin	165..188	CDD:278814	10/22 (45%)
		Calponin	205..228	CDD:278814
		Calponin	245..267	CDD:278814
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578017
Domainoid	1	1.000	83	1.000	Domainoid score	I8268
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D488325at33208
OrthoFinder	1	1.000	-	-		FOG0000270
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X194
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.850