DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mp20 and cnn1a

DIOPT Version :9

Sequence 1:	NP_001014522.2	Gene:	Mp20 / 36468	FlyBaseID:	FBgn0002789	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	NP_001139070.1	Gene:	cnn1a / 567396	ZFINID:	ZDB-GENE-090312-141	Length:	287	Species:	Danio rerio

Alignment Length:	193	Identity:	69/193 - (35%)
Similarity:	108/193 - (55%)	Gaps:	21/193 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LERAVRAKIASKRNPEMDKEAQEWIEAI----IAEKFPAGQSYEDVLKDGQVLCKLINVLSPNAV 63
            |...||.|:|.|.:|:.:::.:.|::.|    :||.|..|      ||||.:||:|||.|.|.:|
Zfish    13 LSADVRNKLAQKYDPQTEEDLRMWVQEITGRTLAENFMEG------LKDGVILCELINKLQPGSV 71

  Fly    64 PKVNSSGGQFKFMENINNFQKALKEYGVPDIDVFQTVDLYEKKDIANVTNTIFALG-----RATY 123
            ||||.|...:..:|||.:|.:|:.|||:...|:|:..||:|..:...|..|:.||.     :..|
Zfish    72 PKVNHSTLNWHKLENITHFVRAIGEYGLKPHDIFEANDLFEDMNHTQVQCTLVALAGLAKTKGFY 136

  Fly   124 KHADFKGPFLGPKPADECKRDFTEEQLKAGQTIVGLQAGSNKGATQAGQ-NLGAGRKILLGKV 185
            ..:|     :|.|.|.:.:|.|..:::|||::|:..|.||||.|:|.|. :.|..|.:...|:
Zfish   137 TKSD-----IGVKYAAKKQRKFNPDKMKAGKSIISQQMGSNKFASQKGMTSYGTRRHLYEPKI 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mp20	NP_001014522.2	SCP1	7..179	CDD:227526	66/181 (36%)
		CH	18..121	CDD:237981	40/111 (36%)
		Calponin	158..178	CDD:278814	9/20 (45%)
cnn1a	NP_001139070.1	SCP1	16..179	CDD:227526	64/173 (37%)
		CH	30..126	CDD:278723	38/101 (38%)
		Calponin	165..188	CDD:278814	9/22 (41%)
		Calponin	205..228	CDD:278814
		Calponin	245..266	CDD:278814
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578016
Domainoid	1	1.000	83	1.000	Domainoid score	I8268
eggNOG	1	0.900	-	-		E1_COG5199
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D488325at33208
OrthoFinder	1	1.000	-	-		FOG0000270
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X194
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.750