DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mp20 and iqgap2

DIOPT Version :9

Sequence 1:	NP_001014522.2	Gene:	Mp20 / 36468	FlyBaseID:	FBgn0002789	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	NP_001121812.1	Gene:	iqgap2 / 563030	ZFINID:	ZDB-GENE-030131-2878	Length:	1680	Species:	Danio rerio

Alignment Length:	143	Identity:	42/143 - (29%)
Similarity:	69/143 - (48%)	Gaps:	21/143 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 KEAQEWIEAIIAEKFPAGQSYEDVLKDGQVLCKLINVLSPNAVPK----------VNSSGGQFKF 75
            :||::|:||.:.|:.|.....|:.|::|..|.||....:|..|.:          ...||..|:.
Zfish    57 EEAKQWMEACLEEQLPPTTELENGLRNGVYLGKLAKFFAPQLVSEKKIYDRDQSWYKLSGLHFRH 121

  Fly    76 MENINNFQKALKEYGVPDIDVFQTVDLYEKKDIANVTNTIFALGRATYKHADFKGPFLGPKPADE 140
            .:|...:.:|::..|:|.|...:|.|:|::|::..|...|.||....||        ||..|..:
Zfish   122 TDNTVQWLRAMESIGLPKIFYPETTDVYDRKNMPKVIYCIHALSLYLYK--------LGIAPQIQ 178

  Fly   141 ---CKRDFTEEQL 150
               .|.|||||::
Zfish   179 DLLGKVDFTEEEI 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mp20	NP_001014522.2	SCP1	7..179	CDD:227526	42/143 (29%)
		CH	18..121	CDD:237981	31/109 (28%)
		Calponin	158..178	CDD:278814
iqgap2	NP_001121812.1	CH	54..169	CDD:237981	31/111 (28%)
		RasGAP	1001..1354	CDD:214617
		RasGAP_IQGAP2	1012..1370	CDD:213333
		RasGAP_C	1463..1602	CDD:281787
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2278
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.030