DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mp20 and cnn2

DIOPT Version :9

Sequence 1:	NP_001014522.2	Gene:	Mp20 / 36468	FlyBaseID:	FBgn0002789	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	NP_998841.1	Gene:	cnn2 / 407907	XenbaseID:	XB-GENE-1005289	Length:	295	Species:	Xenopus tropicalis

Alignment Length:	184	Identity:	63/184 - (34%)
Similarity:	104/184 - (56%)	Gaps:	12/184 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LERAVRAKIASKRNPEMDKEAQEWIEAIIAEKFPAGQSYEDVLKDGQVLCKLINVLSPNAVPKVN 67
            |...||.|:|.|.:|:.:.|.:.|||.:..  ...|..::..||||.:||:|:|.|.|:::||||
Frog    13 LSAEVRNKLAQKYDPQKETELKVWIEEVTG--MSIGPDFQKGLKDGVILCELMNKLRPHSIPKVN 75

  Fly    68 SSGGQFKFMENINNFQKALKEYGVPDIDVFQTVDLYEKKDIANVTNTIFAL-----GRATYKHAD 127
            .|...:..:||::||.||:..||:..:|:|:..||:|..::..|..::.||     .|......|
Frog    76 VSRQNWHQLENLSNFIKAMNLYGMKSVDLFEANDLFENGNMTQVQVSLLALAGLAKSRGMQSEVD 140

  Fly   128 FKGPFLGPKPADECKRDFTEEQLKAGQTIVGLQAGSNKGATQAGQNLGAGRKIL 181
                 :|.|.:::.:|:|.:...|||..::|||.|:||.|:|:|......|:.|
Frog   141 -----IGVKYSEKQERNFDDNTKKAGHCVIGLQMGTNKCASQSGMTAYGTRRHL 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mp20	NP_001014522.2	SCP1	7..179	CDD:227526	60/176 (34%)
		CH	18..121	CDD:237981	36/107 (34%)
		Calponin	158..178	CDD:278814	9/19 (47%)
cnn2	NP_998841.1	SCP1	17..189	CDD:227526	61/178 (34%)
		Calponin	205..228	CDD:366078
		Calponin	244..266	CDD:366078
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H3215
Inparanoid	1	1.050	115	1.000	Inparanoid score	I4677
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D488325at33208
OrthoFinder	1	1.000	-	-		FOG0000270
OrthoInspector	1	1.000	-	-		otm47470
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X194
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060