DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mp20 and cnn3

DIOPT Version :9

Sequence 1:	NP_001014522.2	Gene:	Mp20 / 36468	FlyBaseID:	FBgn0002789	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	NP_989257.1	Gene:	cnn3 / 394869	XenbaseID:	XB-GENE-951266	Length:	331	Species:	Xenopus tropicalis

Alignment Length:	188	Identity:	69/188 - (36%)
Similarity:	109/188 - (57%)	Gaps:	20/188 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LERAVRAKIASKRNPEMDKEAQEWIE----AIIAEKFPAGQSYEDVLKDGQVLCKLINVLSPNAV 63
            |...|:.|||.|.:|::::|.:.|||    .||.|.|..|      |:||.:||.|||.|.|.::
Frog    12 LSAEVKNKIAQKYDPQVEEELRLWIEEVTGMIIGENFQQG------LRDGIILCNLINKLQPGSI 70

  Fly    64 PKVNSSGGQFKFMENINNFQKALKEYGVPDIDVFQTVDLYEKKDIANVTNTIFALG-----RATY 123
            .|:|.:...:..:|||.||.||:::||:...|:|:..||:|..::..|..::.:|.     |..:
Frog    71 KKINEAKLNWHKLENIGNFIKAMQDYGMKPHDIFEANDLFENGNMTQVQTSLVSLAGLAKTRGFH 135

  Fly   124 KHADFKGPFLGPKPADECKRDFTEEQLKAGQTIVGLQAGSNKGATQAGQNLGAGRKIL 181
            ...|     :|.|.|::.||.|.:|::||||:::|||.|:||.|:|||......|:.|
Frog   136 TSVD-----IGVKYAEKQKRQFGDEKMKAGQSVIGLQMGTNKCASQAGMTAYGTRRHL 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mp20	NP_001014522.2	SCP1	7..179	CDD:227526	66/180 (37%)
		CH	18..121	CDD:237981	37/111 (33%)
		Calponin	158..178	CDD:278814	10/19 (53%)
cnn3	NP_989257.1	CH	27..126	CDD:366016	36/104 (35%)
		Calponin	164..187	CDD:366078	11/22 (50%)
		Calponin	204..226	CDD:366078
		Calponin	243..266	CDD:366078
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	115	1.000	Inparanoid score	I4677
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D488325at33208
OrthoFinder	1	1.000	-	-		FOG0000270
OrthoInspector	1	1.000	-	-		otm47470
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2278
SonicParanoid	1	1.000	-	-		X194
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.000