DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mp20 and rng2

DIOPT Version :9

Sequence 1:	NP_001014522.2	Gene:	Mp20 / 36468	FlyBaseID:	FBgn0002789	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	NP_593860.1	Gene:	rng2 / 2543129	PomBaseID:	SPAC4F8.13c	Length:	1489	Species:	Schizosaccharomyces pombe

Alignment Length:	152	Identity:	42/152 - (27%)
Similarity:	73/152 - (48%)	Gaps:	18/152 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KIASKRNPEMD--------KEAQEWIEAIIAEKFPAGQSYEDVLKDGQVLCKLINVLSPNAVPKV 66
            ::|:|:...:.        .||::|||..:........::|..|::|.||..|:....|:.:.|:
pombe    26 RLAAKQRETLQAYDYLCRVDEAKKWIEECLGTDLGPTSTFEQSLRNGVVLALLVQKFQPDKLIKI 90

  Fly    67 -NSSGGQFKFMENINNFQKALKEYGVPDIDVFQTVDLYEKKDIANVTNTIFALGRATY--KHADF 128
             .|:..||:..:|||.|...:...|:|:|..|:..|:||.|::..|...|.||   :|  ...|.
pombe    91 FYSNELQFRHSDNINKFLDFIHGIGLPEIFHFELTDIYEGKNLPKVIYCIHAL---SYFLSMQDL 152

  Fly   129 KGPFLGPKPADECKRDFTEEQL 150
            ..|.:   .:|| ...||:|.:
pombe   153 APPLI---KSDE-NLSFTDEDV 170

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mp20	NP_001014522.2	SCP1	7..179	CDD:227526	42/152 (28%)
		CH	18..121	CDD:237981	32/111 (29%)
		Calponin	158..178	CDD:278814
rng2	NP_593860.1	IQG1	1..1489	CDD:227586	42/152 (28%)
		CH	42..145	CDD:237981	32/105 (30%)
		RasGAP_IQGAP_related	846..1217	CDD:213345
		RasGAP_C	1274..1410	CDD:281787
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	57	1.000	Domainoid score	I3105
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2278
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940