DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mp20 and Tagln

DIOPT Version :9

Sequence 1:	NP_001014522.2	Gene:	Mp20 / 36468	FlyBaseID:	FBgn0002789	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	NP_113737.1	Gene:	Tagln / 25123	RGDID:	3723	Length:	201	Species:	Rattus norvegicus

Alignment Length:	191	Identity:	76/191 - (39%)
Similarity:	109/191 - (57%)	Gaps:	20/191 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LERAVRAKIASKRNPEMDKEAQEWIEAIIAEKFP-AGQ------SYEDVLKDGQVLCKLINVLSP 60
            :.|.|::||..|.:.|:::...||   |:.:..| .|:      .::..||:|.:|.||:|.|.|
  Rat    10 MSREVQSKIEKKYDEELEERLVEW---IVMQCGPDVGRPDRGRLGFQVWLKNGVILSKLVNSLYP 71

  Fly    61 NA-----VPKVNSSGGQFKFMENINNFQKALKEYGVPDIDVFQTVDLYEKKDIANVTNTIFALG- 119
            ..     ||: |.....||.||.:..|.||.::|||...|:||||||:|.||:|.|..|:.|||
  Rat    72 EGSKPVKVPE-NPPSMVFKQMEQVAQFLKAAEDYGVTKTDMFQTVDLFEGKDMAAVQRTVMALGS 135

  Fly   120 -RATYKHADFKG-PFLGPKPADECKRDFTEEQLKAGQTIVGLQAGSNKGATQAGQNLGAGR 178
             ..|.....::| |....|.|.|.||:||:.||:.|:.::|||.|||:||:|||.. |.||
  Rat   136 LAVTKNDGHYRGDPNWFMKKAQEHKREFTDSQLQEGKHVIGLQMGSNRGASQAGMT-GYGR 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mp20	NP_001014522.2	SCP1	7..179	CDD:227526	75/187 (40%)
		CH	18..121	CDD:237981	44/116 (38%)
		Calponin	158..178	CDD:278814	12/19 (63%)
Tagln	NP_113737.1	CH_TAGLN	23..143	CDD:409128	45/123 (37%)
		Could be involved in actin-binding	154..161		3/6 (50%)
		Calponin-like	175..200		14/22 (64%)
		Calponin	175..199	CDD:395325	14/22 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338526
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5199
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D488325at33208
OrthoFinder	1	1.000	-	-		FOG0000270
OrthoInspector	1	1.000	-	-		mtm8915
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X194
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.750