DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mp20 and Cnn1

DIOPT Version :9

Sequence 1:	NP_001014522.2	Gene:	Mp20 / 36468	FlyBaseID:	FBgn0002789	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	XP_011240690.2	Gene:	Cnn1 / 12797	MGIID:	104979	Length:	306	Species:	Mus musculus

Alignment Length:	181	Identity:	72/181 - (39%)
Similarity:	107/181 - (59%)	Gaps:	9/181 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LERAVRAKIASKRNPEMDKEAQEWIEAIIAEKFPAGQSYEDVLKDGQVLCKLINVLSPNAVPKVN 67
            |...|:.|:|.|.:.:.::|.:||||.:...:.  |.::.|.||||.:||:.||.|.|.:|.|||
Mouse    63 LSAEVKNKLAQKYDHQREQELREWIEGVTGRRI--GNNFMDGLKDGIILCEFINKLQPGSVKKVN 125

  Fly    68 SSGGQFKFMENINNFQKALKEYGVPDIDVFQTVDLYEKKDIANVTNTIFALGRATYKHADFKG-- 130
            .|...:..:|||.||.||:.:|||...|:|:..||:|..:...|.:|:.||.    ..|..||
Mouse   126 ESTQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHTQVQSTLLALA----SMAKTKGNK 186

  Fly   131 PFLGPKPADECKRDFTEEQLKAGQTIVGLQAGSNKGATQAGQNL-GAGRKI 180
            ..:|.|.|::.:|.|..|:|:.|:.|:|||.|:||||:|||... |..|:|
Mouse   187 VNVGVKYAEKQERRFEPEKLREGRNIIGLQMGTNKGASQAGMTAPGTKRQI 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mp20	NP_001014522.2	SCP1	7..179	CDD:227526	69/174 (40%)
		CH	18..121	CDD:237981	41/102 (40%)
		Calponin	158..178	CDD:278814	12/20 (60%)
Cnn1	XP_011240690.2	CH_CNN1	76..183	CDD:409131	42/112 (38%)
		Calponin	213..237	CDD:395325	13/23 (57%)
		Calponin	253..276	CDD:395325
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834940
Domainoid	1	1.000	89	1.000	Domainoid score	I7812
eggNOG	1	0.900	-	-		E1_COG5199
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D488325at33208
OrthoFinder	1	1.000	-	-		FOG0000270
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2278
SonicParanoid	1	1.000	-	-		X194
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.780