DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GstE14 and Eef1g

DIOPT Version :9

Sequence 1:	NP_610855.1	Gene:	GstE14 / 36467	FlyBaseID:	FBgn0033817	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_080283.3	Gene:	Eef1g / 67160	MGIID:	1914410	Length:	437	Species:	Mus musculus

Alignment Length:	191	Identity:	46/191 - (24%)
Similarity:	82/191 - (42%)	Gaps:	28/191 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 DFLALNPQHSVPTLVHGD--LVLTDSHAILIHLAEKFDEGGSLWPQEHAERMKVLNLLLFECSFL 109
            :||...|...||.. .||  ..:.:|:||..:::.:...|.:  |:..|:   |:..:.|
Mouse    48 EFLRKFPAGKVPAF-EGDDGFCVFESNAIAYYVSNEELRGST--PEAAAQ---VVQWVSF----- 101

  Fly   110 FRRDSDFMSATVRQGFANVDVAHHERKLTE--------AYIIMERYLENSDFMAGPQLTLADLSI 166
              .|||.:.......|..:.:.||.::.||        ...:::.:|:...|:.|.::||||:::
Mouse   102 --ADSDIVPPASTWVFPTLGIMHHNKQATENAKEEVKRILGLLDTHLKTRTFLVGERVTLADITV 164

  Fly   167 VTTLSTV--NLMFP--LSQFPRLRRWFTAMQQLDAYEANCSGLEKLRQTMESVGSFQFPSS 223
            |.||..:  .::.|  ...||...|||........:.| ..|..||.:.|....:.:|..|
Mouse   165 VCTLLWLYKQVLEPSFRQAFPNTNRWFLTCINQPQFRA-ILGEVKLCEKMAQFDAKKFAES 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE14	NP_610855.1	GstA	6..200	CDD:223698	39/166 (23%)
		GST_N_Delta_Epsilon	6..79	CDD:239343	10/33 (30%)
		GST_C_Delta_Epsilon	94..209	CDD:198287	29/126 (23%)
Eef1g	NP_080283.3	GST_N_EF1Bgamma	4..82	CDD:239342	10/34 (29%)
		GstA	5..202	CDD:223698	39/166 (23%)
		GST_C_EF1Bgamma_like	91..213	CDD:198290	31/132 (23%)
		FinO_conjug_rep	<211..>265	CDD:301594	3/14 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..268		2/4 (50%)
		EF1G	275..381	CDD:279041
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810