DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE14 and GstE12

DIOPT Version :9

Sequence 1:	NP_610855.1	Gene:	GstE14 / 36467	FlyBaseID:	FBgn0033817	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_001246500.1	Gene:	GstE12 / 37960	FlyBaseID:	FBgn0027590	Length:	223	Species:	Drosophila melanogaster

Alignment Length:	216	Identity:	74/216 - (34%)
Similarity:	119/216 - (55%)	Gaps:	9/216 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KPILYYDERSPPVRSCLMLIKLLDIDVELRFVNLFKGEQFQKDFLALNPQHSVPTLVHGDLVLTD 69
            ||.|||...|||.|:.|:..|.:.:|:|||.:||.|||....:||.|||||::|||:.|:..:.|
  Fly     3 KPALYYATLSPPSRAVLLTAKAIGLDLELRPINLLKGEHLTPEFLKLNPQHTIPTLIDGEATIID 67

  Fly    70 SHAILIHLAEKF-DEGGSLWPQEHAERMKVLNLLLFECSFLFRRDSDFMSATVRQGF--ANVDVA 131
            ||||..:|.||: .:...|:|:|..:|..|...|..:...||.|........:..|.  .::|..
  Fly    68 SHAICAYLVEKYGQKEQQLYPKELVQRANVDARLHLDSGHLFARLRFLYEPILYYGSTDCSIDKI 132

  Fly   132 HHERKLTEAYIIMERYLENSDFMAGPQLTLADLSIVTTLSTVNLMFPLSQ--FPRLRRWFTAMQQ 194
            .:.:|..|   |:|.:|::..::.|..||:||...|.|:::||...|:.:  ||::..|...:.:
  Fly   133 AYIQKCWE---ILEGFLKDQPYLCGSDLTIADFCAVATVTSVNDTAPIDEFKFPKMHAWLKRLAE 194

  Fly   195 LDAY-EANCSGLEKLRQTMES 214
            |..| |.|..|.::|:...::
  Fly   195 LPYYQEVNGDGADELKSIFKA 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE14	NP_610855.1	GstA	6..200	CDD:223698	69/199 (35%)
		GST_N_Delta_Epsilon	6..79	CDD:239343	36/72 (50%)
		GST_C_Delta_Epsilon	94..209	CDD:198287	31/119 (26%)
GstE12	NP_001246500.1	GST_N_Delta_Epsilon	4..77	CDD:239343	36/72 (50%)
		GstA	6..201	CDD:223698	68/197 (35%)
		GST_C_Delta_Epsilon	92..210	CDD:198287	31/120 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	9	8.970