Protein Alignment GstE14 and GSTT4

DIOPT Version :10

• Sequence 1: NP_610855.1
• Gene: GstE14 / 36467
• FlyBaseID: FBgn0033817
• Length: 232
• Species: Drosophila melanogaster
• Sequence 2: NP_001345593.1
• Gene: GSTT4 / 25774
• HGNCID: 26930
• Length: 241
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 66/255 - (25%)
• Similarity: 110/255 - (43%)
• Gaps: 57/255 - (22%)

  Fly     8 LYYDERSPPVRSCLMLIKLLDIDVELRFVNLFKGEQFQKDFLALNPQHSVPTLVHGDLVLTDSHA 72
            ||.|..|.|.|:..:..|..||....:||:|.||....|.::.:||...:|:|..|..:|::|.|
Human     5 LYMDLLSAPCRAVYIFSKKHDIQFNFQFVDLLKGHHHSKGYIDINPLRKLPSLKDGKFILSESAA 69

  Fly    73 ILIHLAEKFDEGGSLW--PQEHAERMKV--------------------LNLLLFECSFLFRRDSD 115
            ||.:|..|: ...|.|  |..|| |.:|                    |.||:.:.:      .:
Human    70 ILYYLCRKY-SAPSHWCPPDPHA-RARVDEFVAWQHTAFQLPMKKIVWLKLLIPKIT------GE 126

  Fly   116 FMSATVRQGFANVDVAHHERKLTEAYIIMERYLENSDFMAGPQLTLADLSIVTTLSTVNLMFPLS 180
            .:||...:  ..|:...:..:|.|.|     :|::..|:.|.|::||||     ::.|.:|.|::
Human   127 EVSAEKME--HAVEEVKNSLQLFEEY-----FLQDKMFITGNQISLADL-----VAVVEMMQPMA 179

  Fly   181 -------QFPRLRRWFTAMQQLDAYEANC-SGL-EKLRQTMESVGSFQFPSSSAVVTEKV 231
                   ...:|..|  .||    .|.|. ||| .:....:..:..:.|.:..::|.|.:
Human   180 ANYNVFLNSSKLAEW--RMQ----VELNIGSGLFREAHDRLMQLADWDFSTLDSMVKENI 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstE14	NP_610855.1	GstA	7..200	CDD:440390	58/220 (26%)
GSTT4	NP_001345593.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	3..78	CDD:469754	26/72 (36%)
		GST_C_Theta	91..217	CDD:198292	32/150 (21%)