DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4679 and AT4G11690

DIOPT Version :9

Sequence 1:	NP_610854.1	Gene:	CG4679 / 36466	FlyBaseID:	FBgn0033816	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	NP_192906.1	Gene:	AT4G11690 / 826774	AraportID:	AT4G11690	Length:	566	Species:	Arabidopsis thaliana

Alignment Length:	687	Identity:	132/687 - (19%)
Similarity:	232/687 - (33%)	Gaps:	226/687 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LSRQLRLLPRANI---ACSL---------------SSSGAHYTTAAPAEDAPIEIPNRIERSPTD 49
            :|..||||...|:   |.||               |||..||.|.:             |.|.|.
plant    42 ISILLRLLLSGNLFSHAQSLLLQVISGKIHSQFFTSSSLLHYLTES-------------ETSKTK 93

  Fly    50 ------LLQALASTVARDYTAPHYKYHDDPFLIPMSNAAK--RTYAMSKESGRKAAKWIKEEHRE 106
                  ::.:...:.:.:.:..::....|...:|.||...  .|:.:...|..:...:..|...:
plant    94 FRLYEVIINSYVQSQSLNLSISYFNEMVDNGFVPGSNCFNYLLTFVVGSSSFNQWWSFFNENKSK 158

  Fly   107 LFMHQ-----------EAQPAIEK------------FAPSMV-YTEDSVVDETSLAQLISQGELK 147
            :.:..           || ..|||            |:|::| ||       |.:.....:||::
plant   159 VVLDVYSFGILIKGCCEA-GEIEKSFDLLIELTEFGFSPNVVIYT-------TLIDGCCKKGEIE 215

  Fly   148 DAVLVYNLLEQKGNPISPELKQSLLELVCFHNNQEPIPEEYIEERWFLQNNKRRERSGKTWKDGD 212
            .|..::..:.:.| .::.|...::|....|.|.        ::::.|....|.:|       ||
plant   216 KAKDLFFEMGKLG-LVANERTYTVLINGLFKNG--------VKKQGFEMYEKMQE-------DG- 263

  Fly   213 LAEKLYSEIEPKTPQSYASLIRGMAKYLQCERAYALLQEAGEKQVQLDTNTFNSVIEIVSFLKDT 277
            :...||         :|..::..:.|..:.:.|:.:..|..|:.|..:..|:|::|
plant   264 VFPNLY---------TYNCVMNQLCKDGRTKDAFQVFDEMRERGVSCNIVTYNTLI--------- 310

  Fly   278 AEQRWQLCKDL-LNE-------MSQQKLRPNLGTLNAVLQCISTFGNFKVARAAALQALPEFKQL 334
                ..||::: |||       |....:.|||.|.|.::......|  |:.:|.:|  ..:.|..
plant   311 ----GGLCREMKLNEANKVVDQMKSDGINPNLITYNTLIDGFCGVG--KLGKALSL--CRDLKSR 367

  Fly   335 GVNPSLGSYYYLLIIFCRERGPVSHVIVDILNDISGKEFQIQHPKDTYFFATAMDVCRNHLHDKS 399
            |::|||.:|..|:..|||:            .|.||
plant   368 GLSPSLVTYNILVSGFCRK------------GDTSG----------------------------- 391

  Fly   400 LAKKVDELLHTG-----KNYDLVGDSFKESIYYRNYLALLCQTESTEDFMLSYDLLVPNIYIPEP 459
            .||.|.|:...|     ..|.::.|:|..|......:.|....|...        |||:::
plant   392 AAKMVKEMEERGIKPSKVTYTILIDTFARSDNMEKAIQLRLSMEELG--------LVPDVH---- 444

  Fly   460 GIMEEILRAIEINGAVEYVPRLWSDMVVFDHTHRESLLLYVLRILVDNKPNPDSPAQAQLPEQGA 524
             ....::....|.|.:....||:..||  :.....:.::|...||            ....|..:
plant   445 -TYSVLIHGFCIKGQMNEASRLFKSMV--EKNCEPNEVIYNTMIL------------GYCKEGSS 494

  Fly   525 KVALDMFERVEEAIKRLRKVSFTGQMLGDILTLLVRGGSYEKATEVFAHIDKNQHRIPGTPSLNA 589
            ..||.:.:.:||.                  .|.....||....||.....|::       ....
plant   495 YRALKLLKEMEEK------------------ELAPNVASYRYMIEVLCKERKSK-------EAER 534

  Fly   590 LIE-FVDASVQEKSPSQALFALQYAVENNFDSRELAK 625
            |:| .:|:.:   .||.::.:|....:|  ||...:|
plant   535 LVEKMIDSGI---DPSTSILSLISRAKN--DSHVSSK 566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4679	NP_610854.1	PLN03218	<210..>348	CDD:215636	35/145 (24%)
		PPR repeat	228..255	CDD:276811	4/26 (15%)
		PPR repeat	261..295	CDD:276811	9/41 (22%)
AT4G11690	NP_192906.1	PPR repeat	97..123	CDD:276811	0/25 (0%)
		PPR_2	162..210	CDD:289786	11/55 (20%)
		PPR	164..198	CDD:273253	7/34 (21%)
		PPR repeat	165..192	CDD:276811	5/27 (19%)
		PPR_1	193..224	CDD:289614	9/37 (24%)
		PPR_2	196..245	CDD:289786	11/56 (20%)
		PPR repeat	200..227	CDD:276811	6/33 (18%)
		PPR repeat	233..262	CDD:276811	7/43 (16%)
		PPR	234..267	CDD:273253	8/48 (17%)
		PPR_1	262..295	CDD:289614	8/42 (19%)
		PPR_2	266..315	CDD:289786	12/70 (17%)
		PPR repeat	270..297	CDD:276811	4/26 (15%)
		PPR_1	297..330	CDD:289614	9/45 (20%)
		PPR_2	302..349	CDD:289786	14/59 (24%)
		PPR repeat	305..332	CDD:276811	9/39 (23%)
		PPR_1	332..360	CDD:289614	8/29 (28%)
		PPR_2	336..385	CDD:289786	17/52 (33%)
		PPR repeat	338..367	CDD:276811	8/32 (25%)
		PPR_1	367..400	CDD:289614	16/73 (22%)
		PPR_2	371..420	CDD:289786	19/89 (21%)
		PPR repeat	375..402	CDD:276811	12/67 (18%)
		PPR	409..443	CDD:273253	9/41 (22%)
		PPR repeat	410..437	CDD:276811	6/26 (23%)
		PPR_1	438..470	CDD:289614	7/44 (16%)
		PPR_2	441..490	CDD:289786	10/67 (15%)
		PPR repeat	443..472	CDD:276811	6/35 (17%)
		PPR_1	472..505	CDD:289614	6/44 (14%)
		PPR_2	476..525	CDD:289786	13/78 (17%)
		PPR repeat	478..507	CDD:276811	7/40 (18%)
		PPR repeat	513..542	CDD:276811	7/35 (20%)
		PPR	515..548	CDD:273253	9/42 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910