DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4676 and ZDHHC9

DIOPT Version :9

Sequence 1:	NP_610853.1	Gene:	CG4676 / 36465	FlyBaseID:	FBgn0033815	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_001008223.1	Gene:	ZDHHC9 / 51114	HGNCID:	18475	Length:	364	Species:	Homo sapiens

Alignment Length:	225	Identity:	48/225 - (21%)
Similarity:	82/225 - (36%)	Gaps:	80/225 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ILRSWDRVKPRSISDFACFLLVAVFVPVTYIFHVTIVMPELFAIGGIWYTLLWLASLFLIFN--- 64
            :.|.|:::..|  :.|.|...| :......||::|:            :.:|...:||..|.
Human    10 VTRKWEKLPGR--NTFCCDGRV-MMARQKGIFYLTL------------FLILGTCTLFFAFECRY 59

  Fly    65 ----------ITSNMLACMLVDTSIRKELLKP-------PLDAA--------------------- 91
                      :.:.||....:.|.:|.....|       |.:||
Human    60 LAVQLSPAIPVFAAMLFLFSMATLLRTSFSDPGVIPRALPDEAAFIEMEIEATNGAVPQGQRPPP 124

  Fly    92 ---------QLARWHSCQDCQTLVPPRSWHCEVCNVCVLKRDHHCRFTCCCIGHHNYRYFFYY-- 145
                     |:.:...|..|:...|||:.||.:|:.||.:.||||.:...|:|..|||||:.:
Human   125 RIKNFQINNQIVKLKYCYTCKIFRPPRASHCSICDNCVERFDHHCPWVGNCVGKRNYRYFYLFIL 189

  Fly   146 -------------LVYMIIGSLAAAIMESI 162
                         :||:.:.||....:|::
Human   190 SLSLLTIYVFAFNIVYVALKSLKIGFLETL 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4676	NP_610853.1	zf-DHHC	99..232	CDD:279823	26/79 (33%)
ZDHHC9	NP_001008223.1	DHHC	138..261	CDD:396215	26/82 (32%)
ZDHHC9	NP_001008223.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	303..364
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810