DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG4676 and Zdhhc17

DIOPT Version :9

Sequence 1:NP_610853.1 Gene:CG4676 / 36465 FlyBaseID:FBgn0033815 Length:284 Species:Drosophila melanogaster
Sequence 2:NP_766142.2 Gene:Zdhhc17 / 320150 MGIID:2445110 Length:632 Species:Mus musculus


Alignment Length:234 Identity:60/234 - (25%)
Similarity:92/234 - (39%) Gaps:46/234 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 LLVAVFVPVTYIFHVTIVMPELFAIGGIWYTLLW--LASLFLIFNITSNMLACML-------VDT 77
            |.:.:::...:..:||            |:...|  |..||:.....:|.:|...       .|.
Mouse   358 LPLGIYLATKFWMYVT------------WFFWFWNDLNFLFIHLPFLANSVALFYNFGKSWKSDP 410

  Fly    78 SIRK---ELLKPPLDAAQLARWHS------CQDCQTLVPPRSWHCEVCNVCVLKRDHHCRFTCCC 133
            .|.|   |..|..:  .:||...|      |..|....|.||.||.|||.|:.|.||||.:...|
Mouse   411 GIIKATEEQKKKTI--VELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNC 473

  Fly   134 IGHHNYRYFFYYLVYMIIGSLAAAIMESIYLWHLHL------DIYWRWSTLFTIFAPVVSLMLSP 192
            :|..|:|||..||.:::. .:...|...:..|.||.      |.:|.:.|.....:|.:..|...
Mouse   474 VGAGNHRYFMGYLFFLLF-MICWMIYGCVSYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLN 537

  Fly   193 S-----WESFYLV--IYDLTLLGFAISSLLLVFHWSIFK 224
            |     |.:..|:  :|.:|.||...:..:....:..||
Mouse   538 SVFHFLWVAVLLMCQLYQITCLGITTNERMNARRYKHFK 576

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4676NP_610853.1 zf-DHHC 99..232 CDD:279823 42/139 (30%)
Zdhhc17NP_766142.2 Necessary and sufficient for interaction with DNAJC5 and SNAP25. /evidence=ECO:0000269|PubMed:25253725 11..305
ANK repeat 89..120 CDD:293786
PHA03095 100..>352 CDD:222980
ANK repeat 122..154 CDD:293786
ANK repeat 156..187 CDD:293786
Ank_2 161..255 CDD:372319
ANK repeat 189..221 CDD:293786
ANK repeat 224..255 CDD:293786
DHHC 438..568 CDD:366691 40/130 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5273
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.