DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4676 and Zdhhc4

DIOPT Version :9

Sequence 1:	NP_610853.1	Gene:	CG4676 / 36465	FlyBaseID:	FBgn0033815	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_001013141.1	Gene:	Zdhhc4 / 304291	RGDID:	1308389	Length:	343	Species:	Rattus norvegicus

Alignment Length:	277	Identity:	67/277 - (24%)
Similarity:	107/277 - (38%)	Gaps:	46/277 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 ACFLLVAVFVPVTYIFHVTIVMPEL-FAIGGIWYTLLWLASLFLIFNITSNMLACMLVDTSIRKE 82
            |..||:...|...|.:.|.....|| |::..:....:.|:...:.|.:|.:.....:..|::...
  Rat    70 ALHLLLQGLVYAEYTYEVFSYCRELEFSLPCLLLPYVLLSVNLVFFTLTCSTNPGTITKTNVLLL 134

  Fly    83 LLKPPLDAAQLARWHSCQDCQTLVPPRSWHCEVCNVCVLKRDHHCRFTCCCIGHHNYRYFFYYLV 147
            |.....|.....:...|..|....|.||.||.||:.||.:.||||.:...|||..|..||..||:
  Rat   135 LQVYEFDEVMFPKNSRCSTCDLRKPARSKHCRVCDRCVHRFDHHCVWVNNCIGAWNTGYFLIYLL 199

  Fly   148 YMIIGSLAAAIMESIYLWHL----------HLDIYWRWSTLFTIFAPVVSLMLSPSWESFYLVIY 202
            .:...:...||:.:.:|..|          :||...|:..:.|.|      ::...:.:|..:|:
  Rat   200 TLTASAATIAILSAAFLLRLVAVSNLYQETYLDDLGRFQAVDTGF------LIQHLFLAFPRIIF 258

  Fly   203 DLTLLGFAISSLLLVFHWSIFKSGSVTRERGTRKYDRGLRGNLEMVLGKRMHLTWLSPFLRSDLP 267
               ||||.|...||:..:..|........:.|.::.||             ...|.
  Rat   259 ---LLGFVIVLSLLLAGYLCFALYLAATNQTTNEWYRG-------------DWAWC--------- 298

  Fly   268 HDGMNWEPIAAFSPKEE 284
               .:| |:.|:||..|
  Rat   299 ---QHW-PLVAWSPSAE 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4676	NP_610853.1	zf-DHHC	99..232	CDD:279823	42/142 (30%)
Zdhhc4	NP_001013141.1	zf-DHHC	151..292	CDD:279823	43/149 (29%)
Zdhhc4	NP_001013141.1	Di-lysine motif. /evidence=ECO:0000250\|UniProtKB:Q9NPG8	340..343
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910