DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4676 and Zdhhc25

DIOPT Version :9

Sequence 1:	NP_610853.1	Gene:	CG4676 / 36465	FlyBaseID:	FBgn0033815	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_001034422.1	Gene:	Zdhhc25 / 300323	RGDID:	1598341	Length:	279	Species:	Rattus norvegicus

Alignment Length:	231	Identity:	58/231 - (25%)
Similarity:	104/231 - (45%)	Gaps:	32/231 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 LLWLASLFLIFNITSNM-----LACMLVDTSIRKELLKPPLDAAQLARWHSCQDCQTLVPPRSWH 112
            :|::.:..:||::.:::     |..||.|........:|..|....     |.||::.:|.|:.|
  Rat    65 MLYIVANGMIFHLLASLALVSHLRTMLTDPGSVPLGNRPGPDTVSY-----CPDCRSAIPKRAAH 124

  Fly   113 CEVCNVCVLKRDHHCRFTCCCIGHHNYRYFFYYLVYMIIGSLAAAIMESIYLWHLHLDIYWRWST 177
            |.||..|:.|.||||.:...|:|..|.:||..:::|:.:......::..|.:...:....|..|:
  Rat   125 CAVCKRCIRKNDHHCPWVNNCVGEDNQKYFLLFIMYIGLSGTHVLLLLGIPVLCSYARGEWDSSS 189

  Fly   178 LFTIFAPVVSLMLSPSWESFYLVIYDLTLLGFAISSLLLVFHWSIFKSGSVTRE---RGTRK-YD 238
            ..:..||::.|:|             :.|:||.:||::|........:...|.|   :.|.. .:
  Rat   190 SVSPPAPILFLLL-------------VALMGFVLSSVMLCTQMCTIYTDKTTTELLYQNTHSPGN 241

  Fly   239 RGLRGNLEMVLGKRMHLTWLSPF-----LRSDLPHD 269
            |....||:.:.|..:.|.|||||     .:...||:
  Rat   242 RAKCANLKAICGSHISLAWLSPFHSPEHYKMSEPHN 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4676	NP_610853.1	zf-DHHC	99..232	CDD:279823	36/135 (27%)
Zdhhc25	NP_001034422.1	zf-DHHC	109..230	CDD:279823	35/138 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810